PMID: 6413590Oct 14, 1983Paper

A simple and efficient method for the production of human gamma interferon

Journal of Immunological Methods
I A Braude

Abstract

A method for the production of human gamma interferon (HuIFN-gamma), which is both simple and efficient, has been developed. The 2 co-inducers, A-23187 and mezerein, stimulate human peripheral blood lymphocytes to produce high levels of HuIFN-gamma in both stationary cultures and spinner cultures. The compound 2,2-dimethyl-6,6,7,7,8,8,8-heptafluoro-3,5-octanedione (FOD) has also proven to be a useful co-inducer. The production of HuIFN-gamma appears to occur in at least 2 phases.

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Citations

May 23, 1985·Journal of Immunological Methods·P H Van der MeideH Schellekens
Feb 29, 1988·Biochemical and Biophysical Research Communications·S G LeeW Drohan
Apr 22, 2008·Development and Psychopathology·Tuppett M YatesByron Egeland
Mar 2, 2011·Statistics and Computing·Hua ZhouKenneth Lange
Apr 15, 2021·Journal of Biological Engineering·Oscar Fabian Garcia-AponteBence Kozma

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