PMID: 11325434Apr 28, 2001Paper

A simple cuff electrode for nerve recording and stimulation in acute experiments on small animals

Journal of Neuroscience Methods
Victor B FenikLeszek Kubin

Abstract

We describe a cuff-type electrode specifically designed for recording from, and electrical stimulation of, cut nerves in acute experiments on small animals. Unlike existing designs of cuff electrodes, it is simple to manufacture, inexpensive and takes little time to implant. The electrode was tested on the hypoglossal, phrenic, recurrent laryngeal, and superior laryngeal nerves in anesthetized rats. It provides satisfactory signal-to-noise ratios (3.0+/-0.8 (mean+/-S.D.)) for hypoglossal and 5.4+/-2.1 for phrenic nerve activity and stable recording over the time course of a typical acute experiment. It eliminates or minimizes the problems with recording stability and space availability associated with conventional hook-type electrodes, and reduces experiment preparation time. This should facilitate neurophysiological experiments on small rodents involving complex protocols that include recording from, and/or stimulation of, multiple nerves.

References

May 1, 1990·Journal of Neuroscience Methods·L Quintin
May 1, 1989·Brain Research Bulletin·P J Jüch, R F Minkels
Oct 1, 1966·Electroencephalography and Clinical Neurophysiology·C H Hockman, R M Butler
Apr 1, 1983·Pflügers Archiv : European journal of physiology·J F SauterB Jeanrenaud
Mar 1, 1982·Journal of Neuroscience Methods·C Julien, S Rossignol

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Citations

Jun 6, 2009·Dysphagia·Teresa E LeverAlexander K Murashov
Oct 22, 2011·Journal of Applied Physiology·Georg M StettnerLeszek Kubin
Aug 16, 2005·American Journal of Respiratory and Critical Care Medicine·Victor B FenikLeszek Kubin
Feb 6, 2013·Journal of Controlled Release : Official Journal of the Controlled Release Society·Dorna EsrafilzadehGordon G Wallace
Apr 2, 2011·The Journal of Comparative Neurology·Yoichiro SugiyamaYasuo Hisa
Sep 30, 2014·New Zealand Veterinary Journal·Ph HemsworthA J Tilbrook
Sep 18, 2002·Journal of Applied Physiology·Victor FenikLeszek Kubin

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