A simple method for enhancing cell adhesion to hydroxyapatite surface

Clinical Oral Implants Research
Sergio BertazzoCelso A Bertran

Abstract

Increase cell adhesion on hydroxyapatite (HA) surface, in a simple, fast and inexpensive way. Hydroxyapatite powder was immersed into deionized water for 15 days, dried and pressed into discs. On those discs, pre-osteoblasts cells were cultured for 30 min and 24 h, and adhesion was analyzed by MTT reduction. The results show that HA treatment in equilibrium with water drastically increases cell adhesion when compared with cultures on HA with no treatment. The results also show that one essential factor required for a complete modification of HA is the amount of time of immersion in water. The work presented here suggests a new, simple and effective method to improve the success of different implants. The method is simple, inexpensive and can be used in the daily routine of different contexts where implants are used, from bone substitution to dental procedures.

References

Jan 1, 1993·Journal of Biomedical Materials Research·S R Radin, P Ducheyne
Jul 15, 1997·Journal of Colloid and Interface Science·S V Dorozhkin
Jan 24, 2007·Archives of Oral Biology·H-B Pan, B W Darvell
Sep 14, 2007·Journal of Inorganic Biochemistry·Sergio Bertazzo, Celso A Bertran
Apr 7, 2010·Colloids and Surfaces. B, Biointerfaces·Sergio BertazzoCelso A Bertran

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Citations

Mar 23, 2011·Journal of Materials Science. Materials in Medicine·Thais Accorsi-MendonçaJosé Mauro Granjeiro
Jan 1, 2014·Clinical Implant Dentistry and Related Research·Eitan MijiritskyLiran Levin
Jun 24, 2017·Journal of Biomedical Materials Research. Part a·M C RossiW F Zambuzzi
Mar 29, 2014·Biotechnology and Bioengineering·Sara Gemini-PiperniWillian Zambuzzi
Jan 10, 2012·Clinical Oral Implants Research·Igor Iuco Castro-SilvaJosé Mauro Granjeiro
Dec 21, 2019·Journal of Cellular Physiology·Anderson M GomesWillian F Zambuzzi
Mar 24, 2011·Clinical Oral Implants Research·Willian Fernando ZambuzziJosé Mauro Granjeiro
Oct 15, 2013·Journal of Cellular Biochemistry·Gustavo V O FernandesWillian F Zambuzzi
Feb 26, 2011·Biotechnology and Bioengineering·Willian F ZambuzziJosé M Granjeiro
Mar 28, 2018·Journal of Materials Science. Materials in Medicine·Celio J da Costa FernandesWillian F Zambuzzi
Oct 30, 2020·Frontiers in Bioengineering and Biotechnology·Marcel Rodrigues FerreiraWillian Zambuzzi
May 16, 2020·Materials Science & Engineering. C, Materials for Biological Applications·Suelen C SartorettoWillian F Zambuzzi

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