A simple method for fabricating artificial kidney stones of different physical properties.

Urological Research
Eric EschPei Zhong

Abstract

A simple method for preparing artificial kidney stones with varying physical properties is described. BegoStone was prepared with a powder-to-water ratio ranging from 15:3 to 15:6. The acoustic properties of the phantoms were characterized using an ultrasound transmission technique, from which the corresponding mechanical properties were calculated based on elastic wave theory. The measured parameters for BegoStone phantoms of different water contents are: longitudinal wave speed (3,148-4,159 m/s), transverse wave speed (1,813-2,319 m/s), density (1,563-1,995 kg/m(3)), longitudinal acoustic impedance (4.92-8.30 kg/m(2) s), transverse acoustic impedance (2.83-4.63 kg/m(2) s), Young's modulus (12.9-27.4 GPa), bulk modulus (8.6-20.2 GPa), and shear modulus (5.1-10.7 GPa), which cover the range of corresponding properties reported in natural kidney stones. In addition, diametral compression tests were carried out to determine tensile failure strength of the stone phantoms. BegoStone phantoms with varying water content at preparation have tensile failure strength from 6.9 to 16.3 MPa when tested dry and 3.2 to 7.1 MPa when tested in water-soaked condition. Overall, it is demonstrated that this new BegoStone preparation method can be...Continue Reading

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Citations

Jan 17, 2013·Physics in Medicine and Biology·Jaclyn LautzPei Zhong
Aug 3, 2013·Journal of Endourology·Alexey MartovVladimir Chernenko
Aug 10, 2013·The Journal of the Acoustical Society of America·Nathan B Smith, Pei Zhong
Nov 3, 2015·The Journal of Urology·Peter Kronenberg, Olivier Traxer
Apr 30, 2015·Journal of Endourology·Yaw A NyameManoj Monga
Feb 26, 2015·World Journal of Urology·Ronald SrokaMarkus J Bader
Mar 19, 2014·Proceedings of the National Academy of Sciences of the United States of America·Andreas NeisiusPei Zhong
Aug 16, 2016·Ultrasound in Medicine & Biology·Ying ZhangPei Zhong
Oct 14, 2016·Journal of Endourology·Michele TalsoOlivier Traxer
Nov 26, 2016·International Journal for Numerical Methods in Biomedical Engineering·Kevin G Wang
May 20, 2017·Journal of Endourology·Cayde RitchieD Duane Baldwin
Oct 18, 2018·Journal of Endourology·Brenton WinshipMichael Lipkin
Apr 12, 2020·World Journal of Urology·Markus J BaderUNKNOWN Training and Research in Urological Surgery and Technology (T.R.U.S.T.)-Group
Aug 6, 2020·The Journal of the Acoustical Society of America·Akshay RandadAdam D Maxwell
Apr 14, 2018·Journal of Endourology·Evan C CarlosMichael E Lipkin
Jan 29, 2020·World Journal of Urology·Frédéric PanthierOlivier Traxer
Apr 3, 2020·The Journal of the Acoustical Society of America·Adam D MaxwellOleg A Sapozhnikov
Jan 31, 2021·Journal of Endourology·Derek S HoPei Zhong
Aug 20, 2019·International Journal of Solids and Structures·S CaoK G Wang
Oct 14, 2019·ACS Biomaterials Science & Engineering·Derek S FrankAdam J Matzger
Sep 3, 2021·The Journal of the Acoustical Society of America·Gaoming XiangPei Zhong

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