A simple multiplier to calculate the impact of HDL cholesterol on cardiovascular risk estimation using SCORE

Atherosclerosis
Olivier S DescampsIan Graham

Abstract

The 2011 ESC-EAS guidelines on the management of dyslipidaemias use four separate charts to illustrate the impact of differing HDL cholesterol levels on risk of cardiovascular disease. We developed an easy way to calculate the effects of differing HDL-C levels on risk by deriving HDL and sex specific multipliers and applying these to various reference charts. Of three strategies explored, one based on a low HDL (0.8 mmol/l) reference chart was the simplest and was acceptably accurate. Such an approach simplifies risk estimation by avoiding the need for multiple charts.

References

Jun 6, 2003·European Heart Journal·R M ConroyUNKNOWN SCORE project group
Jun 30, 2011·European Heart Journal·UNKNOWN European Association for Cardiovascular Prevention & RehabilitationUNKNOWN ESC Committee for Practice Guidelines (CPG) 2008-2010 and 2010-2012 Committees

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Citations

Jun 6, 2013·Nature Reviews. Cardiology·Željko Reiner
Dec 18, 2019·Acta Clinica Belgica·Olivier S DescampsGuy De Backer
Oct 17, 2017·Clinical Chemistry and Laboratory Medicine : CCLM·Mauro PanteghiniUNKNOWN Task Force on Performance Specifications in Laboratory Medicine of the European Federation of Clinical Chemistry and Laborat

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