PMID: 6411523Jan 1, 1983Paper

A simple test for lacrimal gland function: a tear lactoferrin assay by radial immunodiffusion

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
P T Janssen, O P van Bijsterveld

Abstract

A radial immunodiffusion assay for tear lactoferrin is described. Tear samples, collected on filter paper discs, could be applied directly to immunodiffusion plates after blotting. In 58 tear samples from healthy subjects an average lactoferrin concentration of 1.42 g/l was found. A high degree of correlation was found between the lactoferrin radial immunodiffusion and the lysozyme agar diffusion assay in a heterogeneous group, ranging from healthy subjects to patients with severe keratoconjunctivitis sicca. A lower limit of normal (0.78 g/l) could be determined for the tear lactoferrin concentration. The assay does not require laboratory facilities and therefore is an easily accessible alternative for or an addition to lacrimal gland function tests currently used.

References

Jan 1, 1976·The British Journal of Ophthalmology·I A Mackie, D V Seal
Jul 1, 1969·Archives of Ophthalmology·O P van Bijsterveld
Sep 1, 1965·Immunochemistry·G ManciniJ F Heremans
Jul 1, 1968·American Journal of Ophthalmology·A T SapseE E Sercarz
Jul 1, 1966·American Journal of Ophthalmology·L T Jones
Jun 1, 1983·Experimental Eye Research·P T Janssen, O P van Bijsterveld
Jan 1, 1981·Current Eye Research·O P van Bijsterveld, P T Janssen
May 20, 1982·Clinica Chimica Acta; International Journal of Clinical Chemistry·P T Janssen, O P van Bijsterveld
Jan 1, 1982·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·G GrabnerT Luger
Aug 10, 1981·Clinica Chimica Acta; International Journal of Clinical Chemistry·P T Janssen, O P Van Bijsterveld
Sep 1, 1980·Ophthalmology·A Jordan, J Baum

❮ Previous
Next ❯

Citations

Jun 1, 1993·International Ophthalmology·F J Holly
Oct 9, 2002·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Julie M Albietz
Oct 1, 1994·Acta Médica Portuguesa·A BritoL S Faro
Jun 1, 1997·The British Journal of Ophthalmology·A A KruizeJ W Bijlsma
May 26, 1999·The British Journal of Ophthalmology·T AbeM Komatsu
Jun 27, 2012·Progress in Retinal and Eye Research·Lei Zhou, Roger W Beuerman
Jun 29, 2004·Progress in Retinal and Eye Research·Michael E Johnson, Paul J Murphy
Aug 23, 2008·Biochimie·J L Flanagan, M D P Willcox
Jan 1, 1988·International Ophthalmology·K E el-RakhawyO P van Bijsterveld
Dec 17, 2005·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Michael Edward Johnson, Paul James Murphy
Aug 27, 2013·Journal of Avian Medicine and Surgery·Maureen MurrayFlorina Tseng
Jun 1, 1996·Current Eye Research·J C MainstoneT R Golding
Sep 2, 2003·European Journal of Ophthalmology·A FüstF H Grus
Jul 20, 1999·Ocular Immunology and Inflammation·A J KlaegerR S Stephens
Sep 14, 2011·Analytical Chemistry·Kelly Karns, Amy E Herr
Aug 28, 2021·Nutrients·Yingqi ZhangJin Zhang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.