A simplified method to integrate metabolic images in stereotactic procedures using a PET/CT scanner

Stereotactic and Functional Neurosurgery
Piero PicozziF Fazio

Abstract

We have developed a method that needs only the computed tomography (CT) indicator box to coregister positron emission tomography (PET) images and integrates this information with magnetic resonance imaging. The study was performed using a PET/CT scanner. A standard CT bed adapter was attached to the scanner couch. Then, the patient, with the Leksell G frame fixed, was positioned into the scanner with the CT indicator box. PET images were acquired using either [18F]fluorodeoxyglucose or [11C]choline as radioisotopes. After acquisition, CT and PET images were exported in DICOM 3 standard and transferred to a dedicated workstation via data link. Homemade software was implemented for multimodal image fusion. PET images were overwritten to their corresponding CT point values using a threshold algorithm, maintaining the stereotactic CT markers. The use of a CT indicator simplifies the procedure, because there is no need for a radioactive solution filling the indicator box. This method was tested first using a phantom and then in patients. The localization accuracy of the PET images is limited only by the slice thickness.

References

Apr 1, 1997·IEEE Transactions on Medical Imaging·F MaesP Suetens
Jun 5, 2003·Journal of Neuro-oncology·M UtriainenH Minn
Oct 8, 2003·International Journal of Radiation Oncology, Biology, Physics·I Frank CiernikGustav K Von Schulthess

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Citations

Dec 19, 2008·Clinical Nuclear Medicine·Giampiero GiovacchiniFerruccio Fazio
May 12, 2009·Academic Radiology·Habib ZaidiMichael Wissmeyer
Jan 1, 2007·PET Clinics·Homer A Macapinlac
Dec 7, 2006·Neuroimaging Clinics of North America·Homer A Macapinlac

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