PMID: 15379024Sep 24, 2004Paper

A simplified model of the source channel of the Leksell Gamma Knife: testing multisource configurations with PENELOPE

Physics in Medicine and Biology
Feras M O Al-Dweri, A M Lallena

Abstract

A simplification of the source channel geometry of the Leksell Gamma Knife (GK), recently proposed by the authors and checked for a single source configuration (Al-Dweri F M O, Lallena A M and Vilches M 2004 Phys. Med. Biol. 49 2687-703), has been used to calculate the dose distributions along the x, y and z axes in a water phantom with a diameter of 160 mm, for different configurations of the Gamma Knife, including 201, 150 and 102 unplugged sources. The code PENELOPE (v. 2001) has been used to perform the Monte Carlo simulations. In addition, the output factors for the 14, 8 and 4 mm helmets have been calculated. The results found for the dose profiles show a qualitatively good agreement with previous ones obtained with EGS4 and PENELOPE (v. 2000) codes and with the predictions of GammaPlan. The output factors obtained with our model agree within the statistical uncertainties with those calculated with the same Monte Carlo codes and with those measured with different techniques. Owing to the accuracy of the results obtained and to the reduction in the computational time with respect to full geometry simulations (larger than a factor 15), this simplified model opens the possibility of using Monte Carlo tools for planning purpo...Continue Reading

References

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Jul 27, 2004·Physics in Medicine and Biology·Feras M O Al-DweriManuel Vilches

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Citations

Aug 21, 2012·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Giuseppe BattistoniAlberto Torresin
Sep 14, 2006·Medical Physics·Aldo BadanoJosep Sempau
Feb 7, 2007·Medical Physics·Jiri TrnkaJaroslav Kluson
Oct 9, 2009·Medical Physics·A MoutsatsosI Seimenis
Dec 14, 2007·Medical Physics·Aldo BadanoJosep Sempau
Jun 9, 2006·Proceedings of the National Academy of Sciences of the United States of America·F Avraham DilmanianDavid J Anschel
Jul 9, 2008·European Journal of Radiology·F Avraham DilmanianDavid J Anschel
Mar 11, 2009·IEEE Transactions on Medical Imaging·Aldo BadanoJosep Sempau
Nov 15, 2012·Journal of Applied Clinical Medical Physics·Gopishankar NatanasabapathiA K Mahapatra
Mar 28, 2008·Physics in Medicine and Biology·J FennerL Walton
Mar 3, 2006·Physics in Medicine and Biology·Aldo Badano, Josep Sempau

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