A simulation study of the effect of lung cancer screening in China, Japan, Singapore, and South Korea

PloS One
Yufan ChenChung Yin Kong

Abstract

More than 50% of the world's lung cancer cases occur in Asia and more than 20% of cancer deaths in Asia are attributable to lung cancer. The U.S. National Lung Screening Trial has shown that lung cancer screening with computed tomography (CT) can reduce lung cancer deaths. Using the Lung Cancer Policy Model-Asia (LCPM-Asia), we estimated the potential mortality reduction achievable through the implementation of CT-based lung cancer screening in China, Japan, Singapore, and South Korea. The LCPM-Asia was calibrated to the smoking prevalence of each of the aforementioned countries based on published national surveys and to lung cancer mortality rates from the World Health Organization. The calibrated LCPM-Asia was then used to simulate lung cancer deaths under screening and no-screening scenarios for the four countries. Using screening eligibility criteria recommended by the U.S. Centers for Medicare & Medicaid Services (CMS), which are based on age and smoking history, we estimated the lung cancer mortality reduction from screening through year 2040. By 2040, lung cancer screening would result in 91,362 life-years gained and 4.74% mortality reduction in South Korea; 290,325 life-years gained and 4.33% mortality reduction in Japa...Continue Reading

References

Jun 27, 2003·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Motoyasu SagawaShigefumi Fujimura
Jun 16, 2004·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Toshimi TakanoNagahiro Saijo
Jul 13, 2004·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Joseph S K AuStephen C K Law
Jan 13, 2006·The Science of the Total Environment·Yu ZhaoJiming Hao
May 21, 2010·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Carolyn M RutterEric J Feuer
Oct 12, 2010·Bulletin of the World Health Organization·Juncheng QianJulia Alison Critchley
May 6, 2011·International Journal of Cancer. Journal International Du Cancer·Niels H H HeegaardCurtis C Harris
Jul 1, 2011·The New England Journal of Medicine·UNKNOWN National Lung Screening Trial Research TeamJoRean D Sicks
Aug 4, 2011·Cancer Research and Treatment : Official Journal of Korean Cancer Association·Kyung Sook LeeEun-Cheol Park
Oct 28, 2011·JAMA : the Journal of the American Medical Association·Martin M OkenUNKNOWN PLCO Project Team
Feb 3, 2012·Cancer Biomarkers : Section a of Disease Markers·Brian M NolenAnna E Lokshin
Mar 17, 2012·Journal of the National Cancer Institute·Suresh H MoolgavkarEric J Feuer
May 17, 2013·Bulletin of the World Health Organization·Ikuko FunatogawaEiji Yano
Jun 12, 2013·Nature Reviews. Clinical Oncology·Lisa Hutchinson
Jul 19, 2013·Cancer Research and Treatment : Official Journal of Korean Cancer Association·Mina SuhJae Kwan Jun
Jan 9, 2014·JAMA : the Journal of the American Medical Association·Marie NgEmmanuela Gakidou
Oct 15, 2014·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Kevin Ten HaafHarry J de Koning
Mar 19, 2015·Lancet·Gonghuan YangXia Wan
Jan 26, 2016·CA: a Cancer Journal for Clinicians·Wanqing ChenJie He
May 10, 2017·Journal of Occupational and Environmental Medicine·Judith M GraberCristine D Delnevo
Nov 10, 2017·MMWR. Morbidity and Mortality Weekly Report·Elyse PhillipsBrian A King
Feb 13, 2018·Clinical and Experimental Otorhinolaryngology·Doh Young Lee, Young Ho Kim
May 29, 2018·Annals of Internal Medicine·Tanner J CaverlyRafael Meza
Jul 3, 2018·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Ji Won LeeJuntae Lim
Jul 28, 2018·Translational Lung Cancer Research·Paul F Pinsky
Sep 29, 2018·Lancet· The Lancet

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