A single center experience of combined liver kidney transplantation

Clinical Transplantation
A MehrabiB M Schmied

Abstract

With advancements in the operative techniques, patient survival following liver transplantation (LTx) has increased substantially. This has led to the acceleration of pre-existing kidney disease because of immunosuppressive nephrotoxicity making additional kidney transplantation (KTx) inevitable. On the other hand, in a growing number of patients on the waiting list to receive liver, long waiting time has resulted in adverse effect of decompensated liver on the kidney function. During the last two decades, the transplant community has considered combined liver kidney transplantation (CLKTx) to overcome this problem. The aim of our study is to present an overview of our experience as well as a review of the literature in CLKTx and to discuss the controversy in this regard. All performed CLKTx (n = 22) at our institution as well as all available reported case series focusing on CLKTx are extracted. The references of the manuscripts were cross-checked to implement further articles into the review. The analyzed parameters include demographic data, indication for LTx and KTx, duration on the waiting list, Model for End-Stage Liver Disease (MELD) score, Child-Turcotte-Pugh (CTP) score, immunosuppressive regimen, post-transplant compl...Continue Reading

References

Jun 27, 1992·Lancet·T E StarzlM Trucco
May 1, 1991·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·M S PolinskyH J Baluarte
Nov 1, 1988·Transplantation·T A GonwaG B Klintmalm
Mar 1, 1986·Annals of Internal Medicine·R W BusuttilL D Memsic
Nov 29, 1973·The New England Journal of Medicine·S IwatsukiT E Starzl
May 12, 1984·Lancet·R MargreiterW Vogel
Jan 1, 1995·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·C HiesseH Bismuth
Jan 1, 1995·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·N V Jamieson
Aug 1, 1996·AORN Journal·L L Ronk, M Ronk
Aug 1, 1997·Transplantation Proceedings·J R LarueH Bismuth
Jun 17, 1998·The Journal of Pediatrics·W G van 't HoffJ V Leonard
Sep 2, 1998·Transplantation Proceedings·M LangP Neuhaus
Sep 2, 1998·Liver Transplantation and Surgery : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·P E MorrisseyR L Jenkins
Sep 12, 1998·Transplantation·D R JeyarajahG B Klintmalm
Dec 5, 1998·Transplantation Proceedings·A K ChuiA G Sheil
May 8, 1999·Journal of the American Society of Nephrology : JASN·A H Wilkinson, D J Cohen
Sep 29, 1999·Transplantation Proceedings·J V TorregrosaF Oppenheimer
Jan 5, 2000·Transplantation Proceedings·B SpechtenhauserR Margreiter
Feb 7, 2001·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·S R EllisD A Kelly
Feb 24, 2001·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·M NakamuraT Agishi
Mar 10, 2001·Clinics in Liver Disease·P T PhamA H Wilkinson
Mar 27, 2001·Transplantation Proceedings·M AmmorB Charpentier
Mar 27, 2001·Transplantation Proceedings·M LangP Neuhaus
Jan 1, 1994·Transplant International : Official Journal of the European Society for Organ Transplantation·E J HadjiyannakisS A Raptis
Sep 27, 2001·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·M J KemperD E Müller-Wiefel
Nov 22, 2001·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·M LangP Neuhaus
Jan 17, 2002·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·M F GagnadouxM Broyer
Feb 28, 2002·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Connie L DavisAlan H Wilkinson
Mar 5, 2002·Transplant International : Official Journal of the European Society for Organ Transplantation·Olivier DetryMichel Meurisse

❮ Previous
Next ❯

Citations

Jul 14, 2012·World Journal of Gastroenterology : WJG·Marek Hartleb, Krzysztof Gutkowski
May 7, 2013·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Hannu Jalanko, Mikko Pakarinen
Jul 21, 2015·Liver International : Official Journal of the International Association for the Study of the Liver·Erwan DumontetSophie Conchon
Sep 12, 2015·Pediatric Transplantation·Rainer Ganschow, Bernd Hoppe
Jun 12, 2012·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·T HibiG W Burke
Aug 9, 2013·Clinical Transplantation·Mohammad GolrizArianeb Mehrabi
Nov 5, 2016·Disease-a-month : DM·Natasha ShahEdgar Lerma
Aug 25, 2010·Current Opinion in Organ Transplantation·Pierre CochatJérôme Harambat
Sep 21, 2016·World Journal of Hepatology·Rohan M ModiKhalid Mumtaz
Jan 23, 2020·Journal of Clinical Laboratory Analysis·Sergey GautierIrina Pashkova
Mar 3, 2020·Pathology International·Rie IrieMureo Kasahara
Nov 9, 2017·Oncotarget·Shih-Ting HuangLong-Bin Jeng

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.