May 7, 2020

Omics BioAnalytics: Reproducible Research using R Shiny and Alexa

BioRxiv : the Preprint Server for Biology
Amrit SinghB. M. McManus


Summary: High-throughput technologies produce complex high-dimensional datasets which are analyzed using a variety of ever-evolving bioinformatics tools. Well-designed web frameworks enable more intuitive and efficient analysis such that less time is spent on coding and more time is spent on interpretation of results and addressing insightful biological questions aided by interactive visualizations. Here, we present Omics BioAnalytics, a full-service Web framework that enables comprehensive, multi-level characterization, analysis, and integration of omics datasets. Blending web-based (R Shiny) and voice-based (Amazon's Alexa) analytics, Omics BioAnalytics can be deployed both by expert computational biologists and non-coding biological domain experts, alike. Our web framework can be utilized to explore complex datasets and identify biosignatures and discriminative biomarkers of health and disease processes, and generate testable hypotheses relating to underlying molecular mechanisms. Availability: Omics BioAnalytics is freely available at and the web app is deployed at The source code for the companion Alexa Skill can be found at h...Continue Reading

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