PMID: 2505464Aug 1, 1989Paper

A single dose of lithium carbonate acutely elevates intact parathyroid hormone levels in humans

Acta Endocrinologica
E W SeelyE M Brown

Abstract

Hyperparathyroidism has been reported in patients receiving lithium therapy, and lithium alters calcium-regulated PTH release in vitro. Previous studies in vivo have used assays which measure fragments of PTH as well as the intact hormone. To determine if lithium acutely elevates intact PTH levels, we studied 9 subjects who received a single oral dose of lithium carbonate (600 mg). Serum levels of intact PTH, ionized calcium, and lithium were measured before, 2 and 14 h after the dose of lithium. PTH levels rose significantly 2 h following the dose of lithium (before 22 +/- 5.0, post 32 +/- 7.3 ng/l, p less than 0.02). PTH levels had returned to baseline at 14 h (22 +/- 3.8 ng/l). There were no significant changes in ionized calcium levels. Therefore, a single oral dose of lithium carbonate acutely elevates intact PTH values in human subjects.

Citations

May 14, 1992·European Journal of Pharmacology·M E Otero Losada, M C Rubio
Jun 7, 2012·Annals of Surgical Oncology·Jennifer L MartiRobert Udelsman
Mar 3, 2009·World Journal of Surgery·Brian D SaundersPaul G Gauger
Jan 30, 2007·Bone·Ingeborg WiltingTjeerd P van Staa
Jul 29, 2010·The British Journal of Surgery·J JärhultJ Nordenström
Mar 3, 2009·Clinical Endocrinology·Signe Engkjaer ChristensenLeif Mosekilde
Sep 12, 2014·Arquivos brasileiros de endocrinologia e metabologia·Thiago Costa de OliveiraFrancisco de Assis Pereira
Feb 23, 1999·The British Journal of Surgery·H AbdullahL Delbridge
Jul 12, 2005·Calcified Tissue International·P VestergaardL Mosekilde
Mar 1, 1996·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·C R McHenry, K Lee
Jan 1, 1992·Annals of Clinical Biochemistry·P J Wood
Jul 2, 2021·Brain and Behavior·Anthony G Pacholko, Lane K Bekar

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Australian and New Zealand Journal of Medicine
R G Larkins
Biochimica Et Biophysica Acta
H N Christensen, M E Handlogten
© 2022 Meta ULC. All rights reserved