A single session of anodal transcranial direct current stimulation applied over the affected primary motor cortex does not alter gait parameters in chronic stroke survivors

Neurophysiologie clinique = Clinical neurophysiology
Thomas CattagniNicolas Roche

Abstract

The excitability of some neural circuits involved in walking and affected in individuals with chronic stroke can be modulated during and/or immediately after anodal transcranial direct current stimulation (a-tDCS). This study was designed to investigate the effects of a-tDCS during and immediately after application on leg muscle activity during gait, and on spatiotemporal and kinematic gait parameters in patients with chronic stroke. This study was randomized, sham-controlled and double-blinded with a cross-over design and included 24 individuals with chronic stroke. Each participant underwent one 30-minute session each of effective a-tDCS at 2mA and sham tDCS. In both sessions, the anode was placed over the leg motor cortex of the affected hemisphere and the cathode over the contralateral orbit. Six gait trials were performed before, during and immediately after each effective/sham tDCS session. Electromyographic activity of leg muscles, as well as spatiotemporal (e.g. gait speed) and kinematic (e.g. peak knee flexion and ankle dorsiflexion in the swing phase of gait) gait parameters were recorded. Genotyping for the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism was undertaken since this gene may influence mot...Continue Reading

References

May 1, 1990·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·M P KadabaM E Wootten
Nov 1, 1987·Electroencephalography and Clinical Neurophysiology·D A Winter, H J Yack
Feb 1, 1987·Physical Therapy·R W Bohannon, M B Smith
Mar 1, 1974·Journal of Biomechanics·D A WinterD A Hobson
Oct 6, 2000·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·H J HermensG Rau
Dec 16, 2000·Journal of Neurology, Neurosurgery, and Psychiatry·P MarqueC F Roques
Oct 29, 2003·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Michael A NitscheWalter Paulus
Jun 15, 2004·Progress in Neurobiology·Judith D Schaechter
Apr 7, 2005·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·Anthony L Ricamato, Joseph M Hidler
Jan 24, 2006·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Prateek C GandigaLeonardo G Cohen
May 19, 2007·Stroke; a Journal of Cerebral Circulation·Arlene SchmidSamuel S Wu
Aug 25, 2007·Experimental Brain Research·Dean T JefferyMonica A Gorassini
Oct 31, 2008·Neurorehabilitation and Neural Repair·Mark G BowdenSteven A Kautz
Nov 28, 2008·Brain : a Journal of Neurology·Jean-Charles LamyRose Katz
Dec 17, 2008·Brain Research Bulletin·Marco Molinari
Jul 9, 2009·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Gowri Jayaram, James W Stinear
Jul 15, 2009·Journal of Neuroengineering and Rehabilitation·Kathryn M SibleyWilliam E McIlroy
Jul 1, 2008·Brain Stimulation·Michael A NitscheAlvaro Pascual-Leone
Oct 22, 2011·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·N RocheR Katz
Dec 8, 2011·Physiotherapy Research International : the Journal for Researchers and Clinicians in Physical Therapy·Allison CooperSusan Richardson
Feb 15, 2012·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·Mark JesunathadasRoger M Enoka
May 4, 2012·Gait & Posture·Emilie HutinNicolas Roche
May 23, 2012·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Neha Bhagchandani, Sheila Schindler-Ivens
Jun 13, 2013·Gait & Posture·I CampaniniB Damiano
Jun 27, 2013·PloS One·Julien BoudarhamRaphael Zory
Jan 24, 2014·PM & R : the Journal of Injury, Function, and Rehabilitation·Birol Balaban, Fatih Tok
Mar 19, 2014·Brain Stimulation·Sarah WiethoffJohn C Rothwell
Mar 19, 2014·Brain Stimulation·Virginia López-AlonsoMiguel Fernández-Del-Olmo
Jul 21, 2015·Annals of Physical and Rehabilitation Medicine·N RocheB Bussel
Nov 26, 2015·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Ryosuke KitataniShigehito Yamada

❮ Previous
Next ❯

Citations

Aug 18, 2020·Journal of Neuroengineering and Rehabilitation·Sangeetha MadhavanDaniel M Corcos

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.