A Skeptical Approach to the Management of Persistent Oral Ulceration in a Child

Case Reports in Pediatrics
Ibrahim KartalAyşegül Yılmaz

Abstract

The diagnosis of oral lesions is sometimes difficult due to both the clinician's limited experience with the conditions that may cause the lesions and their similar appearances, especially in children. Correctly establishing a definitive diagnosis is of major importance to clinicians who manage patients with oral mucosal diseases. In patients with Fanconi anaemia (FA), oral ulcers occur frequently, which are quite variable, and may lead to a misdiagnosis or failure to diagnose. Here, we report the case of a 15-year-old boy who was examined for squamous cell cancer of the tongue and diagnosed as having FA without any haematological manifestations. While surgery could not be done, both radiotherapy and chemotherapy had to be decreased. He died of progressive disease 6 months after the diagnosis. Unexplained ulcers in a child with a duration longer than 2 weeks should be further evaluated, especially for FA, even without the presence of anaemia.

References

Jan 1, 1995·European Journal of Cancer. Part B, Oral Oncology·J P LustigE Sigler
Dec 16, 2000·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·P JansisyanontR A Ord
Dec 21, 2005·International Journal of Paediatric Dentistry·D L C FurlanettoG V A Topping
Jun 10, 2010·The New England Journal of Medicine·K Kian AngMaura L Gillison
Sep 20, 2011·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Gerrit SpanierTorsten E Reichert
Sep 21, 2013·Archives of Disease in Childhood. Education and Practice Edition·Kirsty Le DoareEsse Menson
Dec 10, 2015·Seminars in Cutaneous Medicine and Surgery·Amanda SiuDaniel M Ramos

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BETA
biopsy

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