A small-scale open-label study of the treatment of canine flea allergy dermatitis with fluralaner

Veterinary Dermatology
Petr FisaraJanet von Berky


Fluralaner is an isoxazoline systemic insecticide and acaricide that provides persistent flea-killing activity on dogs for 12 weeks. European and US field studies have shown that fluralaner treatment alleviates the signs of flea allergy dermatitis (FAD) in client-owned dogs. To assess the clinical response in FAD affected dogs over the 12-week period following a single oral fluralaner treatment. Twenty client-owned dogs were diagnosed with FAD on the basis of compatible clinical signs and a positive response in flea antigen tests, using intradermal and or serological methods. An open-label small-scale study with all dogs receiving a single oral fluralaner treatment. All enrolled dogs were diagnosed with FAD and then clinically monitored at 4-week intervals for 12 weeks. Twenty dogs completed the study. All dogs were flea-free at all post-treatment assessments except for one dog that had a single flea at the first post-enrollment assessment at 4 weeks. At the 4-week post-treatment assessment active FAD signs had resolved in all dogs; at 8 weeks post-treatment, two dogs showed mild signs. All clinical signs of FAD had resolved at the final assessment of 12 weeks after treatment. A single administration of fluralaner alleviated or...Continue Reading


Mar 16, 2007·Veterinary Dermatology·Thierry OlivryUNKNOWN International Task Force On Canine Atopic Dermatitis
Sep 12, 2007·Veterinary Dermatology·P B HillJ Rybnicek
Mar 13, 2014·Parasites & Vectors·Susanne KilpMartin C Nuernberger

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