DOI: 10.1101/479113Nov 27, 2018Paper

A SOSEKI-based coordinate system interprets global polarity cues in Arabidopsis

BioRxiv : the Preprint Server for Biology
Saiko YoshidaDolf Weijers

Abstract

Multicellular development requires coordinated cell polarization relative to body axes, and translation to oriented cell division. In plants, it is unknown how cell polarities are connected to organismal axes and translated to division. Here, we identify Arabidopsis SOSEKI (SOK) proteins that integrate apical-basal and radial organismal axes to localize to polar cell edges. Localization does not depend on tissue context, requires cell wall integrity and is defined by a transferrable, protein-specific motif. SOK proteins structurally resemble the DIX oligomerization domain in the animal Dishevelled polarity regulator. The DIX-like domain self-interacts and is required for edge localization and for influencing division orientation. Our work identifies a plant compass, interpreted by SOK proteins. Furthermore, despite fundamental differences, polarity in plants and animals converge upon the same protein domain.

Related Concepts

Cell Division
Cell Wall
Psychological Orientation
Cell Polarity
Arabidopsis thaliana <plant>
Sp3 Transcription Factor
Apical
Local
Drug Interactions
Establishment of Cell Polarity

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