A spatial analysis of genetic structure of human populations in China reveals distinct difference between maternal and paternal lineages

European Journal of Human Genetics : EJHG
Fuzhong XueL Jin

Abstract

Analyses of archeological, anatomical, linguistic, and genetic data suggested consistently the presence of a significant boundary between the populations of north and south in China. However, the exact location and the strength of this boundary have remained controversial. In this study, we systematically explored the spatial genetic structure and the boundary of north-south division of human populations using mtDNA data in 91 populations and Y-chromosome data in 143 populations. Our results highlight a distinct difference between spatial genetic structures of maternal and paternal lineages. A substantial genetic differentiation between northern and southern populations is the characteristic of maternal structure, with a significant uninterrupted genetic boundary extending approximately along the Huai River and Qin Mountains north to Yangtze River. On the paternal side, however, no obvious genetic differentiation between northern and southern populations is revealed.

References

Apr 1, 1967·The Journal of Surgical Research·M S ValiathanW F Ballinger
Jun 19, 1998·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·L B JordeA R Rogers
Sep 30, 1998·Proceedings of the National Academy of Sciences of the United States of America·J Y ChuL Jin
Nov 30, 2000·Proceedings of the National Academy of Sciences of the United States of America·Y C DingY Zhang
Mar 20, 2001·Nature Reviews. Genetics·L Jin, B Su
Aug 2, 2001·American Journal of Human Genetics·T KarafetM F Hammer
Feb 12, 2002·American Journal of Human Genetics·Yong-Gang YaoYa-Ping Zhang
Apr 16, 2002·American Journal of Physical Anthropology·Yong-Gang YaoYa-Ping Zhang
Sep 25, 2002·Molecular Biology and Evolution·Toomas KivisildRichard Villems
Nov 28, 2002·Molecular Ecology·I DupanloupL Excoffier
Sep 24, 2004·Science in China. Series C, Life Sciences·Wen BoXiao Chunjie

❮ Previous
Next ❯

Citations

May 28, 2010·Journal of Human Genetics·Yongbiao ZhangDuen-Mei Wang
Nov 17, 2011·PloS One·Haiyi LouShuhua Xu
Jan 30, 2009·Dento Maxillo Facial Radiology·D S Macdonald-Jankowski, T K Li
Dec 4, 2012·Comptes rendus biologies·Nicolas BrucatoJean-Michel Dugoujon
Apr 13, 2011·American Journal of Physical Anthropology·Da Di, Alicia Sanchez-Mazas
Jan 22, 2010·American Journal of Physical Anthropology·Yinqiu CuiHui Zhou
Mar 26, 2016·Japanese Journal of Ophthalmology·Mikihide OgasawaraKeigo Shikishima
Feb 25, 2010·Current Biology : CB·Mark Stoneking, Frederick Delfin
Apr 7, 2012·Scientific Reports·Yungang HePan-Asia Snp Consortium
Jan 7, 2020·Annals of Human Biology·Weiwei WuDejian Lu
Dec 6, 2019·Frontiers in Molecular Biosciences·Dayan SunJiucun Wang
Nov 11, 2020·Molecular Biology and Evolution·Yun-Hua LoWen-Ya Ko
Dec 10, 2020·Hereditas·Ziqing Pan, Shuhua Xu

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.