A spatio-temporal model for spontaneous thrombus formation in cerebral aneurysms

BioRxiv : the Preprint Server for Biology
O MalaspinasB Chopard

Abstract

We propose a new numerical model to describe thrombus formation in cerebral aneurysms. This model combines CFD simulations with a set of bio-mechanical processes identified as being the most important to describe the phenomena at a large space and time scales. The hypotheses of the model are based on in vitro experiments and clinical observations. We document that we can reproduce very well the shape and volume of patient specific thrombus segmented in giant aneurysms.

Related Concepts

Observational Study
Aneurysm
Anatomical Space Structure
Spatio-Temporal Analysis
Giant Intracranial Aneurysm
Blood Clot
Simulation
Cerebral Aneurysm
Thrombus
In Vitro [Publication Type]

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