A standardized protocol for quantification of saccadic eye movements: DEMoNS

PloS One
J A Nij BijvankL J van Rijn

Abstract

Quantitative saccadic testing is a non-invasive method of evaluating the neural networks involved in the control of eye movements. The aim of this study is to provide a standardized and reproducible protocol for infrared oculography measurements of eye movements and analysis, which can be applied for various diseases in a multicenter setting. Development of a protocol to Demonstrate Eye Movement Networks with Saccades (DEMoNS) using infrared oculography. Automated analysis methods were used to calculate parameters describing the characteristics of the saccadic eye movements. The two measurements of the subjects were compared with descriptive and reproducibility statistics. Infrared oculography measurements of all subjects were performed using the DEMoNS protocol and various saccadic parameters were calculated automatically from 28 subjects. Saccadic parameters such as: peak velocity, latency and saccade pair ratios showed excellent reproducibility (intra-class correlation coefficients > 0.9). Parameters describing performance of more complex tasks showed moderate to good reproducibility (intra-class correlation coefficients 0.63-0.78). This study provides a standardized and transparent protocol for measuring and analyzing sacca...Continue Reading

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Citations

Apr 3, 2019·Investigative Ophthalmology & Visual Science·Jenny A Nij BijvankLaurentius J van Rijn
Jun 11, 2020·Geriatrics·David B Carr, Prateek Grover
Dec 26, 2018·The International Journal of Eating Disorders·Jess Kerr-GaffneyKate Tchanturia
Jul 10, 2020·Behavior Research Methods·Agostino Gibaldi, Silvio P Sabatini
Jan 12, 2021·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·Jenny A Nij BijvankAxel Petzold
Oct 24, 2020·Frontiers in Psychiatry·Yu ImaokaEling D de Bruin
Jun 4, 2019·Journal of the Neurological Sciences·J A Nij BijvankL J Balk
Feb 18, 2020·Vision Research·J A Nij BijvankL J van Rijn

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Methods Mentioned

BETA
infrared oculography

Software Mentioned

SPSS
Eyelink
Matlab
DEMoNS

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