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A statistical approach to finding overlooked genetic associations

BMC Bioinformatics

Oct 23, 2010

Andrew K RiderScott J Emrich

Abstract

Complexity and noise in expression quantitative trait loci (eQTL) studies make it difficult to distinguish potential regulatory relationships among the many interactions. The predominant method of identifying eQTLs finds associations that are significant at a genome-wide level. The vast...read more

Mentioned in this Paper

Plasmodium
Microarray Analysis
Quantitative Trait Loci
Genome
Saccharomyces cerevisiae allergenic extract
Candidate Gene Identification
Statistical Test
Gene Expression
Malaria
Malaria Vaccines
Paper Details
References
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12
  • References11
  • Citations
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A statistical approach to finding overlooked genetic associations

BMC Bioinformatics

Oct 23, 2010

Andrew K RiderScott J Emrich

PMID: 20964847

DOI: 10.1186/1471-2105-11-526

Abstract

Complexity and noise in expression quantitative trait loci (eQTL) studies make it difficult to distinguish potential regulatory relationships among the many interactions. The predominant method of identifying eQTLs finds associations that are significant at a genome-wide level. The vast...read more

Mentioned in this Paper

Plasmodium
Microarray Analysis
Quantitative Trait Loci
Genome
Saccharomyces cerevisiae allergenic extract
Candidate Gene Identification
Statistical Test
Gene Expression
Malaria
Malaria Vaccines

Feeds With Similar Papers

Plasmodium Falciparum

Malaria remains a major cause of morbidity and mortality in the tropics, with the parasite Plasmodium falciparum responsible for the majority of the disease burden. Discover the latest research on Plasmodium falciparum.

Related Papers

Journal of Computational Biology : a Journal of Computational Molecular Cell Biology

Efficiently identifying significant associations in genome-wide association studies

Journal of Computational Biology : a Journal of Computational Molecular Cell BiologySeptember 17, 2013
Emrah Kostem, Eleazar Eskin
Paper Details
References
  • References11
  • Citations
12
  • References11
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.

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