A structural approach to decipher the neurexin and neuroligin splice isoform code

Neuron
Zhiyi Wei, Mingjie Zhang

Abstract

The alternative splicing of neurexins (NRXs) and neuroligins (NLs) has been implicated in specifying synaptic connections. In this issue of Neuron, Koehnke et al. took a structural approach for assessing the contribution of alternative splice isoforms for beta-NRX/NL-mediated synaptic recognition.

Citations

Jul 21, 2020·Translational Psychiatry·Douglas AsedeMcLean M Bolton

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