A study of an intelligent system to support decision making in the management of labour using the cardiotocograph - the INFANT study protocol

BMC Pregnancy and Childbirth
Peter Brocklehurst, INFANT Collaborative Group

Abstract

Continuous electronic fetal heart rate monitoring in labour is widely used but its potential for improving fetal and neonatal outcomes has not been realised. The most likely reason is the difficulty of interpreting the fetal heart rate trace correctly during labour. Computerised interpretation of the fetal heart rate and intelligent decision-support has the potential to deliver this improvement in care. This trial will test whether the addition of decision support software to aid the interpretation of the cardiotocogram (CTG) during labour will reduce the number of 'poor neonatal outcomes' in those women judged to require continuous electronic fetal heart rate monitoring. An individually randomised controlled trial of 46,000 women who are judged to require continuous electronic fetal monitoring in labour. Women admitted to a participating labour ward who are judged to require continuous electronic fetal monitoring, have a singleton or twin pregnancy, are ≥ 35 weeks' gestation, have no known gross fetal abnormality and are ≥ 16 years of age. Triplets or higher order pregnancy, elective caesarean section prior to the onset of labour, planned admission to NICU. Trial interventions: Computerised interpretation of the CTG with decis...Continue Reading

References

Jun 1, 1976·American Journal of Obstetrics and Gynecology·A D HaverkampC Cetrulo
Oct 15, 1976·American Journal of Obstetrics and Gynecology·P RenouC Wood
Oct 1, 1979·British Journal of Obstetrics and Gynaecology·M D Gillmer, D Combe
Jun 15, 1979·American Journal of Obstetrics and Gynecology·A D HaverkampH E Thompson
Jul 1, 1978·American Journal of Obstetrics and Gynecology·I M KelsoI D Cooke
May 26, 1990·BMJ : British Medical Journal·M Ennis, C A Vincent
Jun 1, 1990·British Journal of Obstetrics and Gynaecology·K W MurphyA Turnbull
Oct 1, 1986·European Journal of Obstetrics, Gynecology, and Reproductive Biology·S NeldamJ Hertel
May 1, 1987·Obstetrics and Gynecology·D A LuthyM A Stenchever
Jul 1, 1985·American Journal of Obstetrics and Gynecology·D MacDonaldI Chalmers
May 1, 1985·Early Human Development·M L LeveneT H Williams
Feb 1, 1983·European Journal of Obstetrics, Gynecology, and Reproductive Biology·T K EskesP C Houx
Nov 1, 1981·American Journal of Obstetrics and Gynecology·C WoodI Anderson
Dec 1, 1994·British Journal of Obstetrics and Gynaecology·J WestgateK R Greene
Mar 19, 1994·BMJ : British Medical Journal·G GaffneyA Johnson
Jan 1, 1997·Archives of Disease in Childhood. Fetal and Neonatal Edition·A Johnson
Mar 17, 2000·BMJ : British Medical Journal·J B SextonR L Helmreich
Dec 13, 2000·Statistics in Medicine·J A Barber, S G Thompson
Jun 1, 2001·Journal of the Royal Society of Medicine·P YoungR Johanson
Jul 15, 1963·American Journal of Obstetrics and Gynecology·E H HON
Jun 4, 2004·Developmental Medicine and Child Neurology·Samantha JohnsonJane Schulte
Jul 21, 2006·The Cochrane Database of Systematic Reviews·Z AlfirevicG M L Gyte
Jan 5, 2008·Developmental Medicine and Child Neurology·Samantha JohnsonUNKNOWN Preterm Infant Parenting Study Group

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Citations

Mar 28, 2017·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Meena BhatiaAparna Reddy
Feb 14, 2018·Health Technology Assessment : HTA·Peter BrocklehurstOliver Rivero-Arias
Nov 22, 2018·BJOG : an International Journal of Obstetrics and Gynaecology·P J SteerL Linsell
Apr 24, 2020·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Alice WeeksJan Hodgson
Jun 18, 2017·JMIR Medical Informatics·Michael S BalikuddembeThorkild Tylleskär
Aug 2, 2018·Journal of Obstetrics and Gynaecology of India·Gaurav Shyam Desai
Jan 8, 2020·Fetal Diagnosis and Therapy·Patricia Garcia-CanadillaBart Bijnens

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Methods Mentioned

BETA
feature extraction

Software Mentioned

Windows
INFANT
Stata

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