A study of experimental syringomyelia by scanning electron microscopy

Neurosurgery
P V HallJ Kalsbeck

Abstract

Experimental hydromyelia and syringomyelia, induced by kaolin in dogs, has been investigated by scanning electron microscopy. This study demonstrated that communication between the 4th ventricle and the spinal central canal is normally occluded by a plug of acellular material lying within the central canal. This plug is broken down following the onset of hydrocephalus and communication is rapidly established between the ventricles and the central canal. The canal distends and ruptures dorsally into the spinal gray matter with the development of extensive intramedullary cavities, lined by glial and neuronal elements. The morphological changes demonstrated are consistent with a physical destructive process of the cord resulting from CSF dissection.

Citations

Jan 1, 1989·Acta Neuropathologica·M Shibutani, R Okeda
Oct 1, 1980·Journal of the Neurological Sciences·B Williams, J Bentley
Dec 1, 1981·Surgical Neurology·T W Phillips, G W Kindt
Jul 31, 2018·Neurosurgery·Daniel H FulkersonThomas G Luerssen

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