PMID: 9184321May 31, 1997Paper

A study of genetic association between manic-depressive illness and a highly polymorphic marker from the GABRbeta-1 gene

American Journal of Medical Genetics
R PuertollanoJ Fernández-Piqueras

Abstract

We report on an association study between a tetranucleotide repeat polymorphism in the GABR beta1 gene and manic-depressive illness in a Spanish population. This gene may be an important candidate for bipolar affective disorders since severe GABergic alterations have been described in patients. Although our results do not reveal a clear evidence for association between manic-depressive illness and GABR beta1, we have found significant differences between patients and controls in the female subpopulation.

Citations

Apr 5, 2005·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·M D LundorfO Mors
Jul 31, 2003·Molecular Psychiatry·P BrambillaJ C Soares

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