PMID: 20120859Feb 4, 2010Paper

A study of intratumor microvessel density and lymph node micrometastases of pN0 supraglottic laryngeal squamous cell carcinoma

Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
Binghua LiMingyuan Chen

Abstract

To investigate the correlation between intratumor microvessel density(IMVD) and lymph node micrometastases. IMVD and lymph node micrometastases were stained with CD105 and CK19 antibody by immunohistochemical method of SABC respectively. IMVD marked with CD105 antibody correlated with T stage and lymph node micrometastases (P < 0.01). The result show that IMVD marked with CD105 antibody highly correlated with lymph node micrometastases. It could be a index to evaluate the prognosis of patients with pN0 supraglottic laryngeal squamous cell carcinoma.

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