A study of otoconia of normal mice and shaker mice

Archives of Oto-rhino-laryngology
J T ChouH Scherer

Abstract

Otoconia from the maculae of the utricule and the saccule of normal mice and shaker mice have been examined by means of polarizing microscopy and scanning electron microscopy. X-ray dispersive analysis was used to determine the elements present in the crystals. The otoconia were found to be negative birefringent crystals. They are among the largest crystals found in mammalian tissues, many being 30-50 microns in length and 109-20 microns in diameter. The majority were calcite (calcium carbonate) crystals. Some crystals had a different morphological appearance and contained phosphorus (phosphate compound) as well as calcium. The phosphate content was much less and sometimes absent from utricular otoconia of shaker mice.

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Citations

Jan 1, 1985·Archives of Oto-rhino-laryngology·R C Rouse, L G Johnsson
Mar 30, 2001·European Journal of Biochemistry·X NirmalaF Sehnal
Jan 13, 2019·Microscopy Research and Technique·Hong-Xia YinZhen-Chang Wang

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