A study of simultaneous photolysis and photoaddition reactions of riboflavin in aqueous solution

Journal of Photochemistry and Photobiology. B, Biology
I AhmadFaiyaz H M Vaid

Abstract

The photodegradation reactions of riboflavin (RF) in the presence of 0.05-2.00 M phosphate (pH 7.0) have been studied using a specific multicomponent spectrophotometric method. The reactions involve simultaneous photolysis (intramolecular photoreduction) and photoaddition (intramolecular photoaddition) leading to lumichrome (LC) and cyclodehydroriboflavin (CDRF), respectively, as major products. The contribution of each reaction in the overall photodegradation depends upon the phosphate concentration, i.e., higher the phosphate concentration higher the extent of photoaddition. The apparent first-order rate constants for the photodegradation of RF and for the formation of LC and CDRF at 0.25-2.00 M phosphate concentration range from 0.65 to 3.03 x 10(-2), and from 0.41 to 0.99 x 10(-2) and 0.12 to 1.63 x 10(-2) min(-1), respectively. The second-order rate constants for the phosphate catalysed photodegradation of RF and for the formation of LC and CDRF are 2.12 x 10(-4) and 0.61 x 10(-4) and 1.41 x 10(-4) M(-1)s (-1), respectively. Since the formation of CDRF by photoaddition is catalysed by HPO(4)(2-) ions, it is suggested that H(2)PO(4)(-) ions may be involved in the formation of LC by photolysis. Thus, both H(2)PO(4)(-) and HP...Continue Reading

References

Sep 1, 1975·European Journal of Biochemistry·M Schuman JornsP Hemmerich
Jan 1, 1992·Journal of Pharmaceutical and Biomedical Analysis·I AhmadA A Fareedi
Jan 1, 1990·Journal of Pharmaceutical and Biomedical Analysis·I Ahmad, H D Rapson
Oct 1, 1967·Photochemistry and Photobiology·P S Song, D E Metzler
Oct 1, 1982·Journal of Pharmaceutical Sciences·E DeRitter
Aug 30, 2000·Biochemical Society Transactions·V Massey
Jul 10, 1955·The Journal of Vitaminology·C FUKAMACHI, Y SAKURAI
Nov 19, 2003·European Journal of Biochemistry·Marco H HeftiWillem J H van Berkel

❮ Previous
Next ❯

Citations

Aug 24, 2006·Apoptosis : an International Journal on Programmed Cell Death·Ana Carolina Santos de SouzaCarmen Veríssima Ferreira
Jul 22, 2004·International Journal of Pharmaceutics·Iqbal AhmadQ Nawab Manzar Ali
Jul 29, 2016·Pharmaceutical Development and Technology·Victoria J Valerón Bergh, Hanne Hjorth Tønnesen
Feb 27, 2008·The Journal of Chemical Physics·Laurent GuyonPhilippe Dugourd
Jun 10, 2017·Journal of Photochemistry and Photobiology. B, Biology·Iqbal AhmadSaif-Ur-Rehman Khattak
Apr 4, 2018·Journal of Bacteriology·Hiroshi KanazawaNaoki Takaya
Aug 9, 2015·Applied and Environmental Microbiology·Kazunori Yamamoto, Yasuhisa Asano
Jul 6, 2006·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Iqbal AhmadFaiyaz H M Vaid
Dec 3, 2009·Chemical & Pharmaceutical Bulletin·Iqbal AhmadFaiyaz Hussain Madni Vaid
Oct 27, 2005·Journal of the International Neuropsychological Society : JINS·Leon Y DeouellNachum Soroker
Mar 30, 2010·Attention, Perception & Psychophysics·Sarah ShomsteinMarlene Behrmann
Oct 11, 2014·Chemistry : a European Journal·Małgorzata Insińska-Rak, Marek Sikorski
Jan 22, 2020·Bioscience, Biotechnology, and Biochemistry·Hiroshi KanazawaNaoki Takaya
Sep 24, 2014·Beilstein Journal of Organic Chemistry·Muhammad Ali SherazIqbal Ahmad
Jan 14, 2020·Journal of Photochemistry and Photobiology. B, Biology·Zubair AnwarIqbal Ahmad
Feb 18, 2020·Journal of Photochemistry and Photobiology. B, Biology·Agnieszka Wolnicka-GlubiszAndrzej Zadlo
Jan 4, 2007·Journal of Agricultural and Food Chemistry·Mun Yhung JungDavid B Min
Aug 4, 2021·The Journal of Chemical Physics·Linda GiacomozziMark H Stockett
Jun 27, 2012·The Journal of Physical Chemistry. a·Dorota PrukałaMarek Sikorski
Nov 10, 2018·Environmental Science & Technology·Eric C RybergJae-Hong Kim

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Photochemistry and Photobiology. B, Biology
I AhmadFaiyaz H M Vaid
International Journal of Pharmaceutics
I AhmadQ Nawab Manzar Ali
Journal of Pharmaceutical and Biomedical Analysis
I Ahmad, H D Rapson
© 2022 Meta ULC. All rights reserved