PMID: 9171903Jan 1, 1997Paper

A study of the combined effects of shelf ageing following irradiation in air and counterface roughness on the wear of UHMWPE

Bio-medical Materials and Engineering
A A BesongJ Fisher

Abstract

Damage to polished femoral heads in vivo can cause increased wear of acetabular cups. Oxidation and ageing after sterilisation by gamma irradiation in air, can also change the mechanical properties and wear resistance of ultra high molecular weight polyethylene (UHMWPE). This study investigated the combined effect of these changes in material properties on the wear of UHMWPE for different counterface roughnesses, representative of new femoral heads and those damaged in vivo. Wear rates were studied on a tri-pin-on-disc tribometer in a protein-containing solution. A comparison was made of the wear, using three different counterface roughnesses, of specimens that were manufactured from polyethylene acetabular cups of different shelf ages (3-120 months) after gamma irradiation in air but never implanted. These were compared to the wear of control specimens that were manufactured from cups that had not been sterilised. The wear surfaces were tested 1 mm below the initial articulating surface of the cup, the position of high degradation. The wear rate of UHMWPE which had been sterilised by gamma irradiation in air was shown to increase significantly with ageing time on the shelf for all counterface conditions. The wear rate of all m...Continue Reading

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.