PMID: 6988330Jan 1, 1980Paper

A study of the immunosuppressive effect of allopurinol

Immunological Communications
L H Toledo-Pereyra, R Hoffman


Allopurinol demonstrated to have an immunosuppressive action when given at the dose of 200 microgram daily to the mice receiving skin grafts. This effect was not as apparent in adult mongrel dogs receiving kidney allografts and immediate bilateral nephrectomy. If allopurinol was combined with azathioprine, however, a significant synergistic immunosuppressive effect was seen.


Apr 29, 2000·International Journal of Immunopharmacology·C KatoY Eishi
Dec 1, 1982·Clinical Immunology and Immunopathology·T M EllisT Mohanakumar

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