A study of the mechanical forces on aphakic iris-fixated intraocular lenses

Journal of Biomechanical Engineering
Peyman Davvalo KhongarRodolfo Repetto

Abstract

Iris-fixated aphakic intraocular lenses (IFIOL) are used in cataract surgery, when more common intraocular lenses cannot be adopted because of the absence of capsular bag support. These lenses can be implanted either on the poste- rior or the anterior surface of the iris. In this work we study whether one of these options is preferable over the other from the mechanical point of view. In particular, we focus on the forces that the IFIOL transmits to the iris, which are asso- ciated with the risk of lens dislocation. We study the prob- lem numerically and consider aqueous flow induced by sac- cadic rotations in the cases of an IFIOL in the anterior and posterior side of the iris. The IFIOL considered is the Arti- san Aphakia +30.0 D lens (IFIOL) produced by Ophtec BV. We perform the simulations in OpenFOAM. We find that the forces transmitted by the aphakic IFIOL to the iris are sig- nificantly higher in the case of posterior implantation. This suggests that lens implantation on the posterior surface of the iris might be associated with a higher risk of lens disloca- tion, when an inadequate amount of iris tissue is enclavated during implantation.

References

Apr 15, 1992·American Journal of Ophthalmology·C J PavlinF S Foster
Sep 1, 1956·The British Journal of Ophthalmology·J A BESWICK, C MCCULLOCH
Sep 24, 2005·Physics in Medicine and Biology·Rodolfo RepettoChiara Cafferata
May 16, 2006·Journal of Cataract and Refractive Surgery·Ghee Soon Ang, Ian F Whyte
Mar 22, 2007·Physics in Medicine and Biology·Alessandro StocchinoChiara Cafferata
Sep 13, 2008·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Florian RüferJohann Roider
May 28, 2009·Biomechanics and Modeling in Mechanobiology·R RepettoA Stocchino
Aug 14, 2009·Journal of Biomechanics·Konstantinos KapnisisC Ross Ethier
Aug 23, 2011·Journal of Cataract and Refractive Surgery·Samantha R De SilvaPaul Rosen
Oct 22, 2011·Medical Engineering & Physics·Omid AboualiJiyuan Tu
Apr 10, 2012·Journal of Biomechanical Engineering·Omid AboualiJiyuan Tu
Oct 6, 2012·Journal of Cataract and Refractive Surgery·Johannes GonnermannNecip Torun
Dec 20, 2012·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Johannes GonnermannEckart Bertelmann
Jan 7, 2014·Clinical Ophthalmology·Maurice SchallenbergDaniel Meller
Nov 13, 2014·Current Opinion in Ophthalmology·Augustine R HongAndrew J W Huang
May 30, 2015·Investigative Ophthalmology & Visual Science·Rodolfo RepettoPaolo Soleri
Jan 23, 2016·Ophthalmic Epidemiology·Hassan HashemiAkbar Fotouhi

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