A study of viral hepatitis e infection in a tertiary care hospital in mysore, South India

Open Forum Infectious Diseases
Karkala Achutha Sudharshana MurthyHisham Hakeem

Abstract

In this study, we aimed to explore the clinical and epidemiological profile of all patients with hepatitis E virus (HEV) who were admitted to a tertiary care hospital in Mysore, India and to further assess various factors that influence the prognosis of these patients. Two hundred ninety patients with HEV infection were included in the study and interviewed. They were subjected to clinical examination and laboratory investigations, including complete hemogram, renal, and liver function tests. Viral markers for HBV, HAV, HCV, and HEV by hepatitis B surface antigen, anti-HAV, anti-HCV, and anti-HEV antibodies, respectively, were done using the enzyme-linked immunosorbent assay method. Final outcome was recorded in the form of discharge or death. Males had higher (82.8%) incidence of HEV infection. Yellowish discoloration of urine was the most common symptom, and icterus was the most common sign at presentation. Hepatomegaly was most common finding on abdominal examination. Mean duration of hospital stay was higher among diabetics (10 days vs 7.11 ± 3.52 days). Overall, mortality observed was 3.45%. A higher mean age (P = .000) and duration of hospital stay (P = .000) were associated with higher mortality. Mortality was significan...Continue Reading

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Citations

Dec 18, 2020·Journal of Medical Virology·Abdullah A BakiMustafizur Rahman
Jan 21, 2020·Infectious Disorders Drug Targets·Neelam MehtaSantosh Kumar Singh

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Methods Mentioned

BETA
enzyme-linked immunosorbent assay

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