A study on clinical effect of Arbidol combined with adjuvant therapy on COVID-19.

Journal of Medical Virology
Wenyu ChenZhen Wu

Abstract

This study aims to explore the clinical effect of Arbidol (ARB) combined with adjuvant therapy on patients with coronavirus disease 2019 (COVID-19). The study included 62 patients with COVID-19 admitted to the First Hospital of Jiaxing from January to March 2020, and all patients were divided into the test group and the control group according to whether they received ARB during hospitalization. Various indexes in the two groups before and after treatment were observed and recorded, including fever, cough, hypodynamia, nasal obstruction, nasal discharge, diarrhea, C-reactive protein (CRP), procalcitonin (PCT), blood routine indexes, blood biochemical indexes, time to achieve negative virus nucleic acid, and so on. The fever and cough in the test group were relieved markedly faster than those in the control group (P  <  .05); there was no obvious difference between the two groups concerning the percentage of patients with abnormal CRP, PCT, blood routine indexes, aspartate aminotransferase, and alanine aminotransferase (P > .05); the time for two consecutive negative nucleic acid tests in the test group were shorter than that in the control group; the hospitalization period of the patients in the test group and control group wer...Continue Reading

References

Apr 25, 2003·Lancet·J S M PeirisUNKNOWN SARS study group
Jul 21, 2006·Virology Journal·Yury S BoriskinStephen J Polyak
Jan 16, 2007·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Giuseppe GernaFausto Baldanti
Apr 26, 2007·Biochemistry·Eve-Isabelle PécheurStephen J Polyak
Oct 16, 2007·Clinical Microbiology Reviews·Vincent C C ChengKwok Yung Yuen
Nov 15, 2007·Journal of Paediatrics and Child Health·Astrid VabretFrançois Freymuth
Apr 9, 2008·Current Medicinal Chemistry·Y S BoriskinS J Polyak
Jun 10, 2010·The Journal of Physical Chemistry. B·José Villalaín
Oct 19, 2012·The New England Journal of Medicine·Ali M ZakiRon A M Fouchier
Apr 29, 2014·Antiviral Research·Julie BlaisingEve-Isabelle Pécheur
May 9, 2015·Journal of Immunology Research·Faruku BandeAbdul Rahman Omar
Jan 8, 2016·Journal of Virology·Eve-Isabelle PécheurStephen J Polyak
May 28, 2019·Virology Journal·Dewald Schoeman, Burtram C Fielding
Feb 26, 2020·Journal of Medical Virology·Pengfei SunBo Pan

❮ Previous
Next ❯

Citations

Sep 6, 2020·Military Medical Research·Ying-Hui JinUNKNOWN Chinese Research Hospital Association (CRHA)
Aug 28, 2020·Frontiers in Microbiology·Siew L TeohShaun W H Lee
Jan 27, 2021·Cells·Rameswari Chilamakuri, Saurabh Agarwal
Nov 17, 2020·Frontiers in Immunology·Taylon Felipe SilvaMilena Menegazzo Miranda-Sapla
Oct 30, 2020·Risk Management and Healthcare Policy·Azadeh Teimury, Elahe Mahmoodi Khaledi
Feb 8, 2021·Journal of Pharmaceutical and Biomedical Analysis·Philippe-Henri SecretanBernard Do
Mar 9, 2021·Japan Journal of Nursing Science : JJNS·Lanfang Chu, Yongwen Zhang
Jul 28, 2020·Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy·Sylwester DrożdżalMarek J Łos
Jun 3, 2021·Pharmaceuticals·Ashli M HeustessPius S Fasinu
May 26, 2021·Journal of Medical Virology
Aug 5, 2021·Immunity, Inflammation and Disease·Behnam AmaniMahsa Zareei
Aug 29, 2021·Pharmaceuticals·Victoria Gil MartínezSonia Santander Ballestín

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.