Dec 1, 1977

A surface antigen associated with Hodgkin's disease: brief communication

Journal of the National Cancer Institute
R FavreG Meyer

Abstract

We used an indirect immunofluorescence technique to detect a surface antigen that may be associated with Hodgkin's disease (HD). A heteroantiserum raised in a rabbit given an injection of cells obtained from an HD lymph node (Stage I, classification of Lukes and Butler) allowed us to detect an antigen on the surfaces of HD-derived cells in 25 of 27 instances. Benign and malignant non-HD-type lesions (both lymph node and spleen) did not have this antigen. The nature of this antigen and the type of cells bearing it are unknown.

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Mentioned in this Paper

Hemodialysis
Classification
Spleen
Antigenic Specificity
Injection Procedure
Lymph Nodes
Antigens
Hodgkin Disease
Malignant Neoplasms
Surface

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