A syndrome of the dentate nucleus mimicking psychogenic ataxia

Journal of the Neurological Sciences
Farid SalihChristoph J Ploner

Abstract

To date, cerebellar involvement in control of non-motor functions like cognition and emotion is increasingly well established. Current models suggest that motor and non-motor networks connecting the cerebellum with cortical areas operate independently in closed and segregated loops. Here, we report a 59-year-old female patient with a small cerebellar lesion that shows that cognitive activation can significantly influence cerebellar motor control. Surprisingly, this led to a clinical picture mimicking a psychogenic disorder. Similar to non-human primates, this case suggests that the human dentate nucleus consists of distinct cognitive and motor domains with additional somatotopical arrangement of the latter. Extending current models of cerebro-cerebellar interaction, this case further illustrates that there can be significant functional cross-talk between motor and cognitive cerebellar networks.

References

Oct 1, 1995·Journal of Neurology, Neurosurgery, and Psychiatry·S A FactorE S Molho
May 13, 1998·Brain : a Journal of Neurology·R J Dolan
Jan 11, 2003·Journal of Neurophysiology·Richard P Dum, Peter L Strick
Sep 21, 2004·The Journal of Neuropsychiatry and Clinical Neurosciences·Jeremy D Schmahmann
Dec 7, 2007·Movement Disorders : Official Journal of the Movement Disorder Society·Galit Yogev-SeligmannNir Giladi

❮ Previous
Next ❯

Citations

Sep 4, 2015·Cerebellum & Ataxias·Heike JacobiDagmar Timmann

❮ Previous
Next ❯

Related Concepts

Related Feeds

Ataxia

Ataxia is a neurological condition characterized by lack of voluntary coordination of muscle movements including loss of coordination, balance, and speech. Discover the latest research on ataxia here.

Ataxias (MDS)

Ataxia is a neurological condition characterized by lack of voluntary coordination of muscle movements including loss of coordination, balance, and speech. Discover the latest research on ataxia here.

Ataxias

Ataxia is a neurological condition characterized by lack of voluntary coordination of muscle movements including loss of coordination, balance, and speech. Discover the latest research on different types of ataxias here.