A Systematic Review and Meta-Analysis of Open vs. Laparoscopic Resection of Gastric Gastrointestinal Stromal Tumors

Journal of Clinical Medicine Research
Jean-Sebastien PelletierShahzeer Karmali

Abstract

Gastric gastrointestinal stromal tumors (GISTs) are the most common sarcoma of the gastrointestinal tract, and surgical resection is the primary treatment of early disease. Limited data exist concerning laparoscopic resections of these neoplasms. This systematic review was designed to evaluate the literature comparing laparoscopic and open surgical resection of gastric GISTs and to assess the effectiveness and safety of this minimally invasive technique. We performed a systematic search of MEDLINE, the Cochrane Library, PubMed, Embase, Scopus, Web of Science, Google Scholar, the clinical trials database and ProQuest Dissertations and Theses as well as the past 3 years of conference abstracts from the Society of American Gastrointestinal and Endoscopic Surgeons Annual Meetings. Studies comparing the open and the laparoscopic approaches to the resection of gastric GISTs were included in this systematic review. Two reviewers independently performed the screen of titles and abstracts, the full manuscript review, the data extraction and the risk of bias assessment. A quantitative analysis was performed. Of the 189 studies identified, seven studies were included. The laparoscopic approach was associated with a significantly lower len...Continue Reading

Citations

Mar 24, 2016·Journal of Gastrointestinal Cancer·Syed AsifShivendra Singh
Apr 17, 2018·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Nobutsugu AbeMasanori Sugiyama
Nov 15, 2017·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Xin YeZhigang Xue
Sep 9, 2017·BMC Medical Research Methodology·Mónica BallesterosXavier Bonfill
Sep 4, 2019·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Peter HohenbergerPaolo Casali

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Methods Mentioned

BETA
surgical resection
surgical
dissections
surgical resections

Software Mentioned

Review Manager
Embase
ProQuest
Scopus

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