A systematic review and meta-analysis of cognitive behavioral and psychodynamic therapy for depression in Parkinson's disease patients

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Cheng-Long XieWen-Wen Wang

Abstract

Numerous practice guidelines have recommended cognitive behavioral therapy (CBT) and psychodynamic therapy as a treatment of choice for depression in Parkinson's disease (PD). However, no recent meta-analysis has examined the effects of brief psychotherapy (which includes both CBT and psychodynamic therapy) for adult depression in PD. We decided to conduct such a systematic review and meta-analysis. We included randomized controlled trials (RCTs) examining the effects of brief psychotherapy compared with control groups, other support nursing, or pharmacotherapy. The quality of included studies was strictly evaluated. Twelve studies including 766 patients met all inclusion criteria. The result showed that brief psychotherapy could evidently improve the HAMD (p < 0.00001) and Moca scale (p = 0.006). There was no statistical significance in PDQ-39 scale (p = 0.31). In the subgroup analysis by types of brief psychotherapy, the efficacy of psychodynamic psychotherapy was better than CBT (SMD = -2.02 vs SMD = -0.90) for the outcome measure according to HAMD scale. Meanwhile, we found brief psychotherapy in China was more effective than in US (SMD = -1.54 vs SMD = -1.23), and in low quality studies was more efficacious than in high qu...Continue Reading

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Citations

Mar 25, 2019·Neurology·Karen I ConnorBarbara G Vickrey
Apr 15, 2017·Neurology. Clinical Practice·Zahra Goodarzi, Zahinoor Ismail
Nov 20, 2018·Journal of Korean Medical Science·Ji Won HanJong-Min Kim
Aug 9, 2018·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Giovanni GaleotoGiovanni Fabbrini
Aug 3, 2017·NPJ Parkinson's Disease·Meghan HumbertLana M Chahine
May 7, 2021·Journal of the American Medical Directors Association·Chien-Tai HongTsai-Wei Huang
Nov 12, 2020·Psychology and Psychotherapy·Nicolò ZarottiJane Simpson

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