A systematic review and meta-analysis of prescribing practices of antidepressants in cancer patients

Psycho-oncology
Saira SanjidaJeremy Couper

Abstract

Antidepressants are commonly used for the pharmacological treatment of depression. We aimed to summarise the prevalence of antidepressant prescription to cancer patients, and differences by study or patient characteristics. PubMed, Embase, Web of Science, Scopus and psychINFO were searched using keywords 'psychotropic', 'antidepressants', 'prescription' and 'cancer'. Prevalence of antidepressants, type, dose and follow-up of antidepressants and prescriber details were extracted. Overall, 1537 articles between 1979 and February 2015 were found, 38 met the inclusion criteria and were reviewed according to PRISMA guidelines. The prevalence rate of prescribing antidepressants to cancer patients was 15.6% (95% CI = 13.3-18.3). Prescription was significantly less common in studies from Asia (7.4%; 95% CI = 4.3-12.5), more common in female (22.6%; 95% CI = 16.0-31.0) or breast cancer patients (22.6%; 95% CI = 16.0-30.9). Selective serotonin reuptake inhibitors were the most frequently prescribed antidepressants. General practitioners and psychiatrists, followed by oncologists, were identified as the major providers of antidepressant prescriptions to cancer patients. Few studies reported the exact dose, length of time drugs were prescr...Continue Reading

References

May 1, 1990·Archives of Internal Medicine·E J Pérez-StableY W Ying
Sep 1, 1985·Psychosomatics·R J Goldberg, V Mor
Oct 1, 1985·General Hospital Psychiatry·H JaegerF Brescia
Feb 1, 1995·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·I A JaiyesimiG N Hortobagyi
Jun 1, 1997·Cancer Nursing·S M Valente, J M Saunders
Oct 6, 1997·BMJ : British Medical Journal·M EggerC Minder
Sep 4, 1999·Palliative Medicine·M Lloyd-WilliamsN Rudd
Jan 9, 2001·JAMA : the Journal of the American Medical Association·W BreitbartR Brescia
Apr 30, 2003·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Fredrick D AshburyWilliam S Edell
Sep 6, 2003·BMJ : British Medical Journal·Julian P T HigginsDouglas G Altman
Feb 3, 2004·The British Journal of Psychiatry : the Journal of Mental Science·Tómas HelgasonTómas Zoega
Jun 24, 2004·The Australian and New Zealand Journal of Psychiatry·Peter Ellis, UNKNOWN Royal Australian and New Zealand College of Psychiatrists Clinical Practice Guidelines Team for Depression
Jul 21, 2004·Journal of the National Cancer Institute. Monographs·Donna B Greenberg
Sep 5, 2006·General Hospital Psychiatry·Adedayo A OnitiloLeonard E Egede
Feb 6, 2007·Clinical Practice and Epidemiology in Mental Health : CP & EMH·Veronika MartinTilman Steinert
Feb 7, 2007·Journal of Pain and Symptom Management·Keith G WilsonJennifer J Clinch
May 3, 2008·The American Journal of Psychiatry·Carolyn L Turvey, Dawn M Klein
Aug 24, 2010·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Nada F KhanPeter W Rose
Mar 8, 2011·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Marc DE HertStefan Leucht
Jun 30, 2011·European Journal of Clinical Pharmacology·Christine Y Lu, Elizabeth Roughead
Aug 9, 2011·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Geertruida H de BockLolkje T W de Jong-van den Berg
Sep 10, 2011·Psycho-oncology·Rajeshwari S PunekarJohn R Moran
Mar 7, 2012·Psycho-oncology·Siri BrelinMarianne Jensen Hjermstad
Sep 13, 2012·Depression Research and Treatment·Patricia A FindleyUsha Sambamoorthi
Sep 26, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M Die Trill
Nov 13, 2012·The Australian and New Zealand Journal of Psychiatry·Chris P StephensonIain S McGregor
Nov 15, 2012·Breast Cancer Research and Treatment·Stacie B DusetzinaNancy L Keating
Nov 24, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·J WalkerM Sharpe
Jan 23, 2013·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Chong Guan NgNiek J de Wit

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Citations

Aug 25, 2016·Journal of Cancer Survivorship : Research and Practice·Pierre VergerHélène Verdoux
Jan 9, 2019·Issues in Mental Health Nursing·Veronica DeckerBarbara A Given
Feb 1, 2019·Psycho-oncology·Gaia PocobelliJessica Chubak
Jan 11, 2018·Palliative & Supportive Care·Kjersti Støen GrotmolMarianne Jensen Hjermstad
Jul 15, 2017·Current Opinion in Clinical Nutrition and Metabolic Care·Klaske van NorrenRenger F Witkamp
Sep 21, 2017·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Saira SanjidaMonika Janda
Aug 30, 2018·Molecular and Clinical Oncology·Yessenia BallouBrad A Bryan
May 11, 2017·Current Psychiatry Reports·Rosangela CarusoLuigi Grassi
Oct 4, 2020·Journal of Clinical Medicine·Claudia Trudel-FitzgeraldLaura D Kubzansky
Dec 23, 2017·Annals of Oncology : Official Journal of the European Society for Medical Oncology·L GrassiR Caruso

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