A Systematic Review and Meta-Analysis of Prevalence Studies of Sporadic Inclusion Body Myositis

Journal of Neuromuscular Diseases
Aoife CallanMerrilee Needham

Abstract

Sporadic Inclusion Body Myositis (sIBM) is a rare and slowly progressive debilitating muscle disease with symptoms generally developing≥50 years of age. To conduct a systematic review and meta-analysis of the prevalence of sIBM literature, including a methodological quality assessment of the selected papers. A systematic search of Medline, Embase, Cochrane Database of Systematic Reviews and major Myositis and Neurological conferences was conducted. Articles reporting prevalence and published in English up to March 2017 were assessed for methodology quality using the Loney quality assessment, Downs & Black score, and the Methodological Evaluation of Observational Research checklists. Meta-analyses using random effects were completed on both general population and≥50 years prevalence estimates. 315 articles were retrieved and data were extracted from 10 relevant studies. One study was subsequently excluded due to methodological issues. The meta-prevalence estimate from 9 papers was 24.8/1,000,000 (95% CI: 20.0-29.6). The methodological quality results were consistent across assessment tools with four articles scoring 4 or 5 out of 8 in the Loney assessment. The meta-prevalence of these four articles was 45.6/ 1,000,000 (95% CI: 3...Continue Reading

References

Nov 1, 1995·Annals of Neurology·R C GriggsL P Rowland
Jun 8, 2000·Muscle & Nerve·B A PhillipsF L Mastaglia
Jul 12, 2002·Statistics in Medicine·Julian P T Higgins, Simon G Thompson
Jun 21, 2006·Psychological Methods·Tania B Huedo-MedinaJuan Botella
Sep 26, 2008·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Merrilee NeedhamFrank L Mastaglia
Feb 6, 2009·Annals of Neurology·George Karpati, Erin K O'Ferrall
Jul 15, 2009·Biochimica Et Biophysica Acta·Marjan Huizing, Donna M Krasnewich
Oct 30, 2009·Journal of Neurology, Neurosurgery, and Psychiatry·A A Amato, R J Barohn
Jul 30, 2011·Journal of Neurology·Naoki SuzukiIchizo Nishino
Oct 14, 2011·Brain : a Journal of Neurology·Olivier BenvenisteDavid Hilton-Jones
Jul 19, 2013·Journal of Neurology, Neurosurgery, and Psychiatry·Stefen BradyDavid Hilton-Jones
Nov 26, 2013·Neuromuscular Disorders : NMD·M R Rose, UNKNOWN ENMC IBM Working Group
Jul 30, 2014·Rheumatology·Alain MeyerJean Sibilia
Dec 17, 2014·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Frank L Mastaglia, Merrilee Needham
Dec 23, 2014·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·G C DoblougØ Molberg

❮ Previous
Next ❯

Citations

Feb 12, 2019·Laboratory Investigation; a Journal of Technical Methods and Pathology·Mikayla L HuntleyXinglong Wang
Nov 26, 2019·Rinshō shinkeigaku = Clinical neurology·Madoka Mori-YoshimuraMasashi Aoki
Aug 24, 2017·Current Opinion in Rheumatology·Karsten Schmidt, Jens Schmidt
Apr 8, 2020·Scandinavian Journal of Immunology·Jiuchang ZhangLiming Zhang
Jul 15, 2020·International Journal of Rheumatic Diseases·Anu BalakrishnanLatika Gupta
Aug 24, 2018·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Elie NaddafMazen M Dimachkie
Apr 27, 2019·Frontiers in Immunology·Adam AmlaniMarvin J Fritzler
Mar 7, 2019·Nature Reviews. Rheumatology·Steven A Greenberg
Jun 25, 2020·Journal of Neurology, Neurosurgery, and Psychiatry·Anke RietveldJoost Raaphorst
Jun 28, 2019·Orphanet Journal of Rare Diseases·Naoki SuzukiMasashi Aoki
Feb 11, 2021·BMJ Case Reports·Christina LawSankar Bandyopadhyay
Apr 22, 2021·Neurology·Steven A Greenberg
Sep 18, 2021·Rheumatology·Elie NaddafTeerin Liewluck

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy
biopsies

Software Mentioned

MORE
Excel
OvidSP
Loney

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.