A systematic review of community-based interventions to improve oral chronic disease medication regimen adherence among individuals with substance use disorder

Drug and Alcohol Dependence
Karen M ClementsMichael C Angelini

Abstract

Poor medication adherence has been shown to cause medical complications, death, and increased healthcare costs and may be of particular importance in patients with substance use disorder (SUD). Concerns regarding adherence in this population may influence a healthcare provider's decision to prescribe a medication requiring high adherence. Guidance defining best practices that promote adherence among individuals with SUD is lacking. A review of English articles in Medline and PsycINFO databases, published between October 1, 1994 and October 31, 2017, was conducted in order to identify studies of interventions intended to improve adherence to oral chronic disease medication regimens among patients with SUD. Randomized controlled trials, quasi-experimental study designs, and case series were included. Article quality was assessed. A total of 854 abstracts were retrieved, of which 24 met inclusion criteria. Adherence interventions were categorized as those: 1) addressing the chronic disease state; 2) addressing SUD; or 3) both. Studies varied greatly with respect to intervention length, method of measuring adherence, and quality. Statistically significant improvement in adherence was observed in 12 of 24 studies (50%). Specific int...Continue Reading

Citations

Dec 31, 2019·Journal of Pharmacy Practice·Christopher J DalyDavid M Jacobs
Aug 28, 2020·Journal of the International AIDS Society·Koharu Loulou ChayamaRyan McNeil
May 10, 2019·Frontiers in Public Health·Sherry DerenBei Wu
Sep 20, 2020·Pharmacy : Journal of Pharmacy, Education and Practice·Christopher J DalyDavid M Jacobs
May 25, 2021·Neuromodulation : Journal of the International Neuromodulation Society·Fiene Marie KuijperCasey H Halpern

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