A Systematic Review of Economic Studies Evaluating Ophthalmic Drugs: An Analysis of the Health-state Utilities.

Ophthalmic Epidemiology
Inês RibeiroCarlos Alves

Abstract

To characterize the techniques used to derive health-state utilities (HSU) in the cost-utility studies (CUS) of ophthalmic drugs. A systematic review was conducted in Pubmed/Embase until October 2019. CUS evaluating ophthalmic drugs were included. Therapeutic area, technique to derive HSU and sources of HSU were extracted. It was assessed if the HSU and the other parameters of CUS were collected from the same population. The techniques to derive HSU used in the CUS were compared to the techniques recommended by the country-specific economic evaluation guidelines. Seventy CUS were included. Forty-three (61.4%) used direct techniques to derive HSU, 19 (27.1%) used indirect, 1 (1.4%) used direct and indirect and the remaining (n = 7; 10.0%) used other or unknown techniques. Twelve (17.1%) CUS collected the HSU and the other parameters from the same population: nine (12.9%) retrieved utility data from experimental studies, two (2.9%) from observational and one (1.4%) from other sources. Forty-eight (68.6%) CUS collected the HSU and the other parameters from different populations: eight (11.4%) retrieved utility data from experimental studies, 33 (47.1%) from observational, one (1.4%) from both experimental and observational and six...Continue Reading

References

Nov 14, 1997·Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association·R D Moore, R E Chaisson
Jan 15, 2000·Archives of Ophthalmology·G C BrownJ Kistler
Mar 5, 2002·Annals of the Rheumatic Diseases·S E GabrielM Drummond
Jun 11, 2005·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Sanjay SharmaGaurav K Shah
Oct 27, 2005·Investigative Ophthalmology & Visual Science·Roseanne MisajonJill Keeffe
Apr 14, 2007·The British Journal of Ophthalmology·James RafteryAndrew Lotery
Apr 26, 2007·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·C BachertP B Poulsen
Jan 9, 2008·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Jonathan C JavittAnthony P Adamis
Jun 25, 2008·Cost Effectiveness and Resource Allocation : C/E·Susan F HurleyRobyn H Guymer
Jan 27, 2009·Clinical Therapeutics·Luis Javier Hernandez-PastorJoaquin Giraldez
Mar 11, 2009·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Michael DrummondUNKNOWN Consensus Development Group
Mar 4, 2009·Investigative Ophthalmology & Visual Science·Ivan J SuñerNeil M Bressler
Jun 6, 2009·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Carolyn Czoski-MurrayHyong Kwon Kang
Jun 23, 2009·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Nalin PayakachatJames G Anderson
Jul 23, 2009·Annals of Internal Medicine·David MoherUNKNOWN PRISMA Group
Aug 12, 2009·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Luis Javier Hernández-PastorJoaquín Giráldez
Dec 2, 2009·Ophthalmology·Richard GrieveUNKNOWN Verteporfin Photodynamic Therapy Cohort Study Group
Dec 5, 2009·Gaceta sanitaria·Julio López BastidaJaume Puig-Junoy
Jul 16, 2010·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·William HodgeAndra Morrison
Aug 12, 2010·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Minjie ChenJia He
Sep 18, 2010·Journal of Evaluation in Clinical Practice·Jignesh J PatelAnthony P Morreale
Apr 22, 2011·Ophthalmology·William E Smiddy
Dec 30, 2011·Investigative Ophthalmology & Visual Science·Eva K FenwickEcosse L Lamoureux
Feb 1, 2012·Acta Ophthalmologica·Aukje van GestelJan S Schouten
Feb 22, 2012·Health Technology Assessment : HTA·B C ReevesU Chakravarthy
Jan 26, 2013·Health and Quality of Life Outcomes·Andrew J LloydAndreas Pleil

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