Abstract
To comparatively evaluate hypertonic sodium (HTS) and mannitol in patients following acute traumatic brain injury (TBI) on the outcomes of all-cause mortality, neurological disability, intracranial pressure (ICP) change from baseline, ICP treatment failure, and serious adverse events. PubMed, EMBASE, CENTRAL, Cochrane Database of Systematic Reviews, ClinicalTrials.gov, and WHO ICTRP (World Health Organization International Clinical Trials Registry Platform) were searched (inception to November 2015) using hypertonic saline solutions, sodium chloride, mannitol, osmotic diuretic, traumatic brain injury, brain injuries, and head injury. Searches were limited to humans. Clinical practice guidelines and bibliographies were reviewed. Prospective, randomized trials comparing HTS and mannitol in adults (≥16 years) with severe TBI (Glasgow Coma Scale score ≤8) and elevated ICP were included. ICP elevation, ICP reduction, and treatment failure were defined using study definitions. Of 326 articles screened, 7 trials enrolling a total of 191 patients met inclusion criteria. Studies were underpowered to detect a significant difference in mortality or neurological outcomes. Due to significant heterogeneity and differences in reporting ICP ch...Continue Reading
References
Jun 1, 1997·Journal of the American Society of Nephrology : JASN·P VisweswaranT D Dubose
Jan 1, 1997·Acta neurochirurgica·A I MaasA Unterberg
Jun 27, 2001·Neurology·B Mokri
Jun 10, 2003·Critical Care Medicine·Renaud VialetClaude Martin
Sep 6, 2003·BMJ : British Medical Journal·Julian P T HigginsDouglas G Altman
Jan 13, 2005·Critical Care Medicine·Claire BattisonThomas Petty
Nov 10, 2005·Critical Care : the Official Journal of the Critical Care Forum·Lilit HarutjunyanJens Soukup
Nov 24, 2006·The Journal of Head Trauma Rehabilitation·Wesley Rutland-BrownYongli Lily Xi
May 22, 2007·Journal of Neurotrauma·Susan L BrattonDavid W Wright
May 25, 2007·Neurocritical Care·Miriam M TreggiariJacques-Andre Romand
Jan 23, 2008·Critical Care Medicine·Gilles FranconyJean-Francois Payen
Sep 23, 2008·Intensive Care Medicine·Carole IchaiXavier Leverve
Nov 27, 2008·The Journal of Head Trauma Rehabilitation·Eduard ZaloshnjaAnbesaw W Selassie
Jul 22, 2009·PLoS Medicine·David MoherUNKNOWN PRISMA Group
Nov 23, 2010·Journal of Neurosurgery·Nikolaos SakellaridisVasiliki Karaouli
Jan 19, 2011·Critical Care Medicine·Hooman KamelNerissa U Ko
Jul 27, 2011·Journal of Neurotrauma·Vincent CottenceauJean Francois Soustiel
Sep 29, 2011·Journal of Neurosurgery·Martin M MortazaviWinfield Fisher
Oct 20, 2011·BMJ : British Medical Journal·Julian P T HigginsUNKNOWN Cochrane Statistical Methods Group
Jul 3, 2013·Emergency Medicine Journal : EMJ·A C RickardC Mann
Apr 24, 2014·PloS One·Elyse Berger PelletierAlexis F Turgeon
Apr 24, 2015·Medicine·Shaw-Ruey LyuChia-Chen Hsu
Citations
Nov 30, 2016·Critical Care Clinics·Deborah M SteinLena M Napolitano
Nov 30, 2016·The Surgical Clinics of North America·Mary K ArbuthnotIan C Glenn
Aug 2, 2017·Journal of Neurosurgical Anesthesiology·Achmet AliIbrahim O Akinci
Aug 18, 2017·International Journal of Molecular Sciences·Annabel J Sorby-AdamsRenée J Turner
Dec 17, 2017·British Journal of Clinical Pharmacology·Georgia TsaousiFederico Bilotta
Sep 19, 2017·Expert Review of Neurotherapeutics·Lisa A DelSignore, Robert C Tasker
Jun 16, 2018·Neurosurgical Review·Jiajie GuHongwu Xu
Jan 27, 2017·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Adrian WongSarah Day
Apr 14, 2019·Transfusion·Peter A AbdelmalikGeoffrey S F Ling
Jun 29, 2018·Journal of Neurosurgical Anesthesiology·Weiliang ZhangLingzhong Meng
Dec 31, 2019·The Cochrane Database of Systematic Reviews·Han ChenJane A Dennis
Jan 25, 2020·The Cochrane Database of Systematic Reviews·Han ChenJane A Dennis
Feb 9, 2020·BMJ Open·Rafael BadenesFerrán Catalá-López
Sep 15, 2016·Oncotarget·Jia ShiSuinuan Wang
Sep 12, 2020·Seminars in Respiratory and Critical Care Medicine·Shayan RakhitMayur B Patel
May 23, 2020·Journal of Anesthesia·Theodoros SchizodimosNikos Kapravelos
Jul 10, 2019·Journal of Neurotrauma·James R AnsteyUNKNOWN TBI Collaborative
Sep 27, 2018·Fluids and Barriers of the CNS·Eva Kjer OernboNanna MacAulay
Feb 6, 2020·CJEM·Laurel Murphy
Nov 7, 2019·The Neurologist·Thomas LawsonMichel T Torbey
Jun 18, 2019·Current Surgery Reports·Henry W Caplan, Charles S Cox
Jul 8, 2020·International Journal of Environmental Research and Public Health·Agnieszka WiórekŁukasz J Krzych
Oct 1, 2019·Journal of Neurosurgical Anesthesiology·Franz SchwimmbeckLeopold Eberhart
Sep 6, 2020·Injury·S F BergmansS M Bossers
Apr 9, 2021·Acta neurologica Belgica·Nir ShimonyGeorge I Jallo
Apr 27, 2021·Neurologic Clinics·Courtney E TakahashiAnna M Cervantes-Arslanian
May 22, 2021·Frontiers in Pharmacology·Barbara GierlikowskaUrszula Demkow
Mar 1, 2020·Current Treatment Options in Neurology·Benjamin E ZusmanRuchira M Jha
Jul 14, 2021·Scientific Reports·Arnošt MládekOndřej Bradáč
Jul 27, 2021·Frontiers in Veterinary Science·Armi Pigott, Elke Rudloff