A systematic review of structural MRI biomarkers in autism spectrum disorder: A machine learning perspective

International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience
Alex M PagnozziStephen E Rose

Abstract

Autism Spectrum Disorder (ASD) affects approximately 1% of the population and leads to impairments in social interaction, communication and restricted, repetitive behaviours. Establishing robust neuroimaging biomarkers of ASD using structural magnetic resonance imaging (MRI) is an important step for diagnosing and tailoring treatment, particularly early in life when interventions can have the greatest effect. However currently, there is mixed findings on the structural brain changes associated with autism. Therefore in this systematic review, recent (post-2007), high-resolution (3 T) MRI studies investigating brain morphology associated with ASD have been collated to identify robust neuroimaging biomarkers of ASD. A systematic search was conducted on three databases; PubMed, Web of Science and Scopus, resulting in 123 reviewed articles. Patients with ASD were observed to have increased whole brain volume, particularly under 6 years of age. Other consistent changes observed in ASD patients include increased volume in the frontal and temporal lobes, increased cortical thickness in the frontal lobe, increased surface area and cortical gyrification, and increased cerebrospinal fluid volume, as well as reduced cerebellum volume and ...Continue Reading

References

Sep 1, 1981·Journal of Autism and Developmental Disorders·B E Hetzler, J L Griffin
Oct 10, 1995·Proceedings of the National Academy of Sciences of the United States of America·M B MoserR G Morris
Aug 1, 1993·Archives of Neurology·J L Cummings
Aug 1, 1996·Child Development·L BennettoS J Rogers
Nov 15, 1996·Science·L C Katz, C J Shatz
Jan 1, 1997·Hippocampus·K HenkeH G Wieser
Jan 23, 1999·Current Opinion in Neurobiology·T J Ebner
Jan 11, 2000·IEEE Transactions on Medical Imaging·K Van LeemputP Suetens
Mar 17, 2000·Brain Research. Brain Research Reviews·F A Middleton, P L Strick
Jun 22, 2000·NeuroImage·J Ashburner, K J Friston
Aug 10, 2000·Novartis Foundation Symposium·P Rakic
Sep 23, 2000·The Journal of Neuropsychiatry and Clinical Neurosciences·M RapoportH Mayberg
Feb 13, 2002·Neurology·Manuel F CasanovaEmil Roy
Apr 12, 2002·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Tony Charman, Gillian Baird
Jun 8, 2002·Annual Review of Neuroscience·Mark G Packard, Barbara J Knowlton
Jul 24, 2002·Neurology·E H AylwardN Singh
Dec 31, 2002·JAMA : the Journal of the American Medical Association·Eric Fombonne
Jul 17, 2003·JAMA : the Journal of the American Medical Association·Eric CourchesneNatacha Akshoomoff
Oct 2, 2003·Brain Research Bulletin·Paolo BrambillaFrancesco Barale
Jan 20, 2004·Neuroscience Letters·Vijendra K Singh, Wyatt H Rivas
Oct 27, 2004·NeuroImage·Stephen M SmithPaul M Matthews
Jan 25, 2005·Pediatric Neurology·Yulia A DementievaMichael L Cuccaro
Sep 6, 2005·Pediatric Neurology·Andrew W ZimmermanMelvyn P Heyes
Dec 7, 2005·Archives of General Psychiatry·Heather Cody HazlettJoseph Piven
Jun 13, 2006·Research in Developmental Disabilities·Johnny L Matson, Marie S Nebel-Schwalm
Aug 22, 2006·Biological Psychiatry·Mark BaradBeat Lutz
Dec 27, 2006·Brain Research·James R BoothTali Bitan
Apr 4, 2007·Archives of Pediatrics & Adolescent Medicine·Lisa A CroenJudith K Grether
Apr 11, 2007·Journal of the American Academy of Child and Adolescent Psychiatry·Cinnamon S Bloss, Eric Courchesne
Jun 15, 2007·Pediatric Neurology·Michael G ChezMatt Kominsky
Sep 4, 2007·European Psychiatry : the Journal of the Association of European Psychiatrists·Andrew C StanfieldStephen M Lawrie
Oct 26, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Christine Wu NordahlDavid C Van Essen
Dec 25, 2007·Journal of Autism and Developmental Disorders·Christine Wu NordahlDavid G Amaral
Feb 9, 2008·Trends in Neurosciences·David G AmaralChristine Wu Nordahl
Mar 21, 2008·Nature Reviews. Neuroscience·Sarah-Jayne Blakemore
Apr 17, 2008·Clinical Child Psychology and Psychiatry·Judith A ReavenRandal G Ross
May 30, 2008·Psychiatry Research·Antonio Y HardanJeffrey A Stanley
Oct 24, 2008·American Journal of Epidemiology·Maureen S DurkinLaura A Schieve

❮ Previous
Next ❯

Citations

Apr 26, 2020·Brain and Behavior·Annika LindUNKNOWN PIPARI Study Group
Jun 15, 2019·AJNR. American Journal of Neuroradiology·M J HochT M Shepherd
Sep 26, 2020·Artificial Intelligence in Medicine·Elisa FerrariAlessandra Retico
Feb 27, 2021·Autism Research : Official Journal of the International Society for Autism Research·Marilena M DeMayoAdam J Guastella
May 1, 2021·Brain Sciences·Marcello ZanghieriDaniel Remondini
May 28, 2021·Journal of Autism and Developmental Disorders·James C McPartlandDominic A Trevisan
Mar 12, 2021·Brain : a Journal of Neurology·Clara A MoreauSebastien Jacquemont
Jun 15, 2021·Computational Intelligence and Neuroscience·Sergio Leonardo MendesJoão Ricardo Sato
Sep 10, 2021·Molecular Psychiatry·Simone ChiolaAleksandr Shcheglovitov
Oct 29, 2021·Scientific Reports·Jürgen GermannGabriel A Devenyi
Jan 19, 2022·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Dominic Dwyer, Nikolaos Koutsouleris
Feb 1, 2022·Human Brain Mapping·Nagehan Demirci, Maria A Holland

❮ Previous
Next ❯

Related Concepts

Related Feeds

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.

Amygdala: Sensory Processes

Amygdalae, nuclei clusters located in the temporal lobe of the brain, play a role in memory, emotional responses, and decision-making. Here is the latest research on sensory processes in the amygdala.

Amygdala and Midbrain Dopamine

The midbrain dopamine system is widely studied for its involvement in emotional and motivational behavior. Some of these neurons receive information from the amygdala and project throughout the cortex. When the circuit and transmission of dopamine is disrupted symptoms may present. Here is the latest research on the amygdala and midbrain dopamine.

Autism

Autism spectrum disorder is associated with challenges with social skills, repetitive behaviors, and often accompanied by sensory sensitivities and medical issues. Here is the latest research on autism.