A Systematic Review of Surgical interventions for the Treatment of Bladder Pain Syndrome/Interstitial Cystitis.

European Urology Focus
Nadir I OsmanChristopher R Chapple

Abstract

Bladder pain syndrome/interstitial cystitis (BPS/IC) is a poorly understood chronic debilitating condition. Surgery is reserved for severe refractory cases; however, there is no consensus on patient selection or optimal approach. To evaluate the evidence relating to the safety and efficacy of surgical interventions for treating BPS/IC. PubMed and Scopus databases were searched for original studies, using keywords "cystectomy", "interstitial cystitis", and "bladder pain syndrome". Articles were reviewed and screened by three independent reviewers. A total of 450 patients were identified from 20 eligible studies: mean age was 54.5 yr and 90.2% were female. The median duration of symptoms preoperatively was 60 mo (range 9-84), with a mean follow-up of 45.5 mo. A total of 448 patients underwent surgery: subtotal cystectomy with cystoplasty (48.6%), cystectomy and orthotopic neobladder (21.9%), cystectomy and ileal conduit (11.2%), and urinary diversion only (18.3%). Symptomatic improvement occurred in 77.2%, with higher rates in the total cystectomy and orthotopic neobladder group. Thirty-one patients (6.9%) required secondary total cystectomy and/or ileal conduit diversion; 48.4% subsequently improved. Seventeen studies reported 1...Continue Reading

References

Aug 1, 1991·British Journal of Urology·D E NurseA R Mundy
Jan 1, 1995·Neurourology and Urodynamics·H D FloodE J McGuire
Aug 1, 1995·British Journal of Urology·O D HughesK C Vaughton
Jan 1, 1995·The Journal of Urology·D E Bejany, V A Politano
Jul 1, 1996·British Journal of Urology·T J ChristmasW F Hendry
Mar 4, 2000·The Australian and New Zealand Journal of Surgery·A J CostelloD Agarwal
Jun 18, 2002·BMJ : British Medical Journal·Peter McCullochDamian Griffin
Feb 1, 2003·Urology·Paul AbramsUNKNOWN Standardisation Sub-Committee of the International Continence Society
Dec 11, 2003·The Journal of Urology·J Kellogg Parsons, C Lowell Parsons
Jun 9, 2004·European Urology·Aniruddha ChakravartiMalcolm Anthony Jones
Sep 5, 2007·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Wachira KochakarnWipaporn Pummangura
Jul 23, 2009·Annals of Internal Medicine·David MoherUNKNOWN PRISMA Group
Aug 4, 2009·BMJ : British Medical Journal·Serge P MarinkovicStuart L Stanton
Sep 8, 2009·European Urology·Magnus FallUNKNOWN European Association of Urology
Dec 22, 2009·Neurourology and Urodynamics·Philip HannoUNKNOWN Bladder Pain Syndrome Committee of the International Consultation on Incontinence
Mar 29, 2012·Scandinavian Journal of Urology and Nephrology·Aage Valdemar AndersenLars Frich
Nov 19, 2013·The Journal of Urology·Jørgen Nordling, Jerry G Blaivas
May 9, 2014·International Journal of Urology : Official Journal of the Japanese Urological Association·Jane M Meijlink
May 9, 2014·International Journal of Urology : Official Journal of the Japanese Urological Association·Hyung Joon KimKyu-Sung Lee
May 9, 2014·International Journal of Urology : Official Journal of the Japanese Urological Association·Naoki Yoshimura
Jul 16, 2014·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Seema A TirlapurUNKNOWN EBM-CONNECT Collaboration
Mar 8, 2017·International Urology and Nephrology·Mohamed H KamelRodney Davis

❮ Previous
Next ❯

Citations

Oct 9, 2020·Journal of Cellular and Molecular Medicine·Xin WangQingjiang Jin
Nov 24, 2020·International Immunopharmacology·Xin WangQingjiang Jin
Oct 28, 2021·Lower Urinary Tract Symptoms·Yoshiyuki AkiyamaYukio Homma

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.