A systematic review of the associations between maternal nutritional biomarkers and depression and/or anxiety during pregnancy and postpartum

Journal of Affective Disorders
Janet TrujilloGilberto Kac

Abstract

Nutritional requirements need to be met in order to adapt to pre- and postnatal changes. Our aim was to systematically review the evidence of associations between nutritional biomarkers and psychological distress during pregnancy and in the first postnatal year. MEDLINE, EMBASE, PsycINFO, Scielo, LILACS, clinicaltrials.gov, International Clinical Trials Registry, Cochrane Library, Scopus and Web of Science databases were searched for articles from inception to 4/15/2016. Studies of maternal nutritional biomarkers in blood (fatty acids/micronutrients/amino acids) and associations with psychological distress (depression/anxiety/stress) were included. Two independent reviewers extracted data based on study designs, participants, outcomes, exposures, and association measures. Thirty-eight studies were included. A total of 13 studies showed divergent or no associations between serum/plasma/erythrocyte fatty acid concentrations and depression/anxiety during pregnancy and postpartum. Changes in serum cholesterol levels from pregnancy to postpartum showed a significant inverse correlation with depression in one out of three studies. Five out of seven studies found an inverse association between serum vitamin D levels and pre- and postn...Continue Reading

Citations

Oct 17, 2018·International Journal of Environmental Research and Public Health·Stefan PilzWinfried März
Jul 10, 2020·International Journal of Molecular Sciences·Elke HumerThomas Probst
Oct 11, 2020·International Journal of Environmental Research and Public Health·Shahirose Sadrudin PremjiMiGHT Maternal-Infant Global Health Team-Collaborators In Research
Oct 5, 2019·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Sohrab IranpourSiamak Sabour
Nov 17, 2020·Frontiers in Psychiatry·Susan ThomasKrishnamachari Srinivasan

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