A Systematic Review of the Existing Prostate Imaging Reporting and Data System Version 2 (PI-RADSv2) Literature and Subset Meta-Analysis of PI-RADSv2 Categories Stratified by Gleason Scores

AJR. American Journal of Roentgenology
Emil Jernstedt BarkovichAntonio C Westphalen

Abstract

The objective of this study was to quantitatively and qualitatively assess the methodologic heterogeneity of the current Prostate Imaging Reporting and Data System version 2 (PI-RADSv2) literature and estimate the proportions of Gleason scores (GSs) diagnosed across PI-RADSv2 categories. This study was a systematic review and meta-analysis and was performed in concordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Only English-language studies and studies published before April 1, 2018, were assessed. The primary outcome of the meta-analysis was the estimated percentage of patients with GS ≥ 3 + 4 within each individual PI-RADSv2 score. We calculated the pooled estimates and 95% CIs on the basis of a random-effects model using the meta-analysis routine of Stata (version 13.1). Our search revealed 434 titles, and 59 of these studies were selected. These studies were remarkable for their technical and terminological diverseness. Thirteen studies had sufficient data to be included in the meta-analysis. The prevalence of ≥ GS 3 + 4 in lesions assigned a PI-RADSv2 score of 3 or higher was approximately 45%. Lesions assigned PI-RADSv2 scores 1 or 2, 3, 4, and 5 represented high-gr...Continue Reading

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Citations

Apr 4, 2020·Journal of Medical Imaging and Radiation Oncology·Wei Che TsaiMartin Schultz
Jul 23, 2020·Nature Reviews. Urology·David Eldred-EvansHashim U Ahmed
Dec 11, 2019·Abdominal Radiology·Prasad R ShankarMark A Helvie
Nov 25, 2020·Radiology·Clare M C Tempany-AfdhalJeffrey Weinreb
Apr 14, 2021·Journal of the American College of Radiology : JACR·Matthew S DavenportPrasad R Shankar
Apr 21, 2021·European Urology Focus·Jost von HardenbergUNKNOWN GESRU Academics Prostate Cancer Group in cooperation with the Working Group of Focal and Microtherapy of the German Society
Nov 15, 2021·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Dariya I MalyarenkoThomas L Chenevert
Jan 17, 2022·The International Journal of Medical Robotics + Computer Assisted Surgery : MRCAS·Peter SparwasserHendrik Borgmann

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