A systematically collated library of prescribing safety indicators for people with chronic kidney disease.

BMC Nephrology
Fiona SmithFergus Caskey

Abstract

People with chronic kidney disease (CKD) have high levels of co-morbidity and polypharmacy placing them at increased risk of prescribing-related harm. Tools for assessing prescribing safety in the general population using prescribing safety indicators (PSIs) have been established. However, people with CKD pose different prescribing challenges to people without kidney disease. Therefore, PSIs designed for use in the general population may not include all PSIs relevant to a CKD population. The aim of this study was to systematically collate a library of PSIs relevant to people with CKD. A systematic literature search identified papers reporting PSIs. CKD-specific PSIs were extracted and categorised by Anatomical Therapeutic Chemical (ATC) classification codes. Duplicate PSIs were removed to create a final list of CKD-specific PSIs. Nine thousand, eight hundred fifty-two papers were identified by the systematic literature search, of which 511 proceeded to full text screening and 196 papers were identified as reporting PSIs. Following categorisation by ATC code and duplicate removal, 841 unique PSIs formed the final set of CKD-specific PSIs. The five ATC drug classes containing the largest proportion of CKD-specific PSIs were: Card...Continue Reading

References

Sep 6, 2013·The New England Journal of Medicine·Michael G ShlipakUNKNOWN CKD Prognosis Consortium
Apr 2, 2014·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Rachel SpencerStephen M Campbell
Apr 10, 2015·Seminars in Dialysis·Thomas D Nolin
Dec 2, 2015·BMC Nephrology·Simon D S FraserMaarten W Taal
Nov 4, 2016·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Kirsten P J SmitsPetra Denig
May 26, 2017·International Journal of Clinical Practice·Wubshet Hailu TesfayeSyed Tabish R Zaidi
Oct 12, 2017·BMC Geriatrics·Nashwa MasnoonGillian E Caughey
Aug 16, 2018·British Journal of Clinical Pharmacology·Solène M LavilleUNKNOWN Chronic Kidney Disease-Renal Epidemiology and Information Network (CKD-REIN) Study Collaborators
Jun 17, 2020·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Samantha HaywardUNKNOWN EQUAL Study investigators

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Methods Mentioned

BETA
pharmacotherapy

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