A Systemic Review on Aloe arborescens Pharmacological Profile: Biological Activities and Pilot Clinical Trials

Phytotherapy Research : PTR
Abdel-Naser B SingabJilan A Nazeam

Abstract

Since ancient times, plants and herbal preparations have been used as medicine. Research carried out in the last few decades has verified several such claims. Aloe arborescens Miller, belonging to the Aloe genus (Family Asphodelaceae), is one of the main varieties of Aloe used worldwide. The popularity of the plant in traditional medicine for several ailments (antitumor, immunomodulatory, antiinflammatory, antiulcer, antimicrobial and antifungal activity) focused the investigator's interest on this plant. Most importantly, the reported studies have shown the plant effectiveness on various cancer types such as liver, colon, duodenal, skin, pancreatic, intestinal, lung and kidney types. These multiple biological actions make Aloe an important resource for developing new natural therapies. However, the biological activities of isolated compounds such as glycoprotein, polysaccharides, enzyme and phenolics were insufficient. Considering all these, this contribution provides a systematic review outlining the evidence on the biological efficacy of the plant including the pharmacology and the related mechanisms of action, with specific attention to the various safety precautions, and preclinical and clinical studies, indicating the fut...Continue Reading

References

Jan 1, 1979·Journal of Biochemistry·I SuzukiT Takahashi
Sep 1, 1977·Zeitschrift Für Naturforschung. Section C: Biosciences·T Hirata, T Suga
Nov 1, 1990·Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan·Y SatoM Shinoda
May 1, 1989·Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan·H SaitoS Okabe
Jun 1, 1984·Journal of Ethnopharmacology·A de Pasquale
Mar 7, 2000·Current Medicinal Chemistry·V E Ooi, F Liu
Nov 10, 2000·Toxicon : Official Journal of the International Society on Toxinology·S M Rates
Aug 26, 2003·European Journal of Clinical Pharmacology·Mats BergströmBengt Långström
Dec 20, 2005·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·H BeppuH Kuzuya
Nov 6, 2007·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Yoko MatsudaKatsumi Imaida
Feb 19, 2011·BMC Complementary and Alternative Medicine·Mary A Bisi-JohnsonSandeep D Vasaikar
Jan 26, 2013·International Journal of Sport Nutrition and Exercise Metabolism·Piotr BastaAnna Skarpańska-Stejnborn
Mar 9, 2013·Fish & Shellfish Immunology·S PicchiettiA M Fausto
Dec 26, 2013·International Journal of Systematic and Evolutionary Microbiology·Hairong HeWensheng Xiang

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Citations

Oct 8, 2016·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Maryam AkaberiSeyed Ahmad Emami
Jul 13, 2018·Critical Reviews in Food Science and Nutrition·Yan GaoRuibing Wang
Sep 22, 2018·International Journal of Molecular Sciences·Bahare SalehiJavad Sharifi-Rad
Jun 23, 2020·Topics in Magnetic Resonance Imaging : TMRI·Kai J BormStephanie E Combs
Apr 18, 2017·Journal of Medicinal Food·Jilan A NazeamAbdel-Naser B Singab
Oct 18, 2020·Tissue Engineering. Part B, Reviews·Jiaheng LiangJingan Li
Dec 15, 2020·BMC Complementary Medicine and Therapies·Ana LimaRicardo Boavida Ferreira
Jun 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Kamil PawłowiczJudyta Cielecka-Piontek

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