A Taiwanese population-based study on the association between chronic tonsillitis and tonsil cancer

Oncotarget
Shih-Han HungHerng-Ching Lin

Abstract

Although it is known that inflammatory processes elevate the risk of cancer, to date the association between chronic tonsillitis and tonsil cancer remains unknown. This study aimed to evaluate the association of chronic tonsillitis with tonsil cancer based on a population-based database in Taiwan. We retrieved data for this study from the Longitudinal Health Insurance Database 2005. This case-control study included 489 patients with tonsil cancer and 2445 matched controls. We used conditional logistic regression analyses to calculate the odds ratio (OR) and corresponding 95% confidence interval (CI) for having been previously diagnosed with chronic tonsillitis between patients with tonsil cancer and the controls. We found that of the 2934 sampled patients, 22 (0.75%) had received a diagnosis of chronic tonsillitis. A Chi-squared test further revealed that there was a significant difference in the prevalences of prior chronic tonsillitis between tonsil cancer patients and controls (2.45% vs. 0.41%,p<0.001). The conditional logistic regression suggested that after adjusting for hypertension, diabetes, hyperlipidemia, obesity, tobacco use disorder, and alcohol abuse/alcohol dependency syndrome, the OR of having previously been dia...Continue Reading

References

Nov 1, 1990·The New England Journal of Medicine·A EkbomH O Adami
May 1, 1989·Archives of Otolaryngology--head & Neck Surgery·J L Brandsma, A L Abramson
Apr 1, 1988·Oral Surgery, Oral Medicine, and Oral Pathology·K H Kassim, T D Daley
Dec 1, 1993·International Journal of Epidemiology·E VesterinenA Aromaa
Nov 1, 1995·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Y C KoC C Tsai
Jun 30, 2000·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·M BoudaC Kittas
Sep 20, 2001·International Immunopharmacology·F A Fitzpatrick
Aug 19, 2003·Archives of Biochemistry and Biophysics·Hiroshi OhshimaTomohiro Sawa
Nov 1, 1957·Cancer·E L WYNDERR M FELDMAN
Jul 9, 2004·International Journal of Pediatric Otorhinolaryngology·Taner YilmazH Tanju Besler
Dec 8, 2004·Cancer Detection and Prevention·Helmut Bartsch, Jagadeesan Nair
Mar 1, 2005·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Aimee R KreimerSilvia Franceschi
Mar 9, 2007·The American Journal of Clinical Nutrition·Ananda S PrasadLavoisier J Cardozo
Mar 27, 2007·Nature Reviews. Cancer·Angelo M De MarzoWilliam G Nelson
Dec 7, 2007·Experimental Gerontology·Ananda S Prasad
Dec 30, 2008·Auris, Nasus, Larynx·Tatjana CvetkovićMilan Stanković
Feb 15, 2011·Future Virology·Vonetta M WilliamsPenelope J Duerksen-Hughes
Oct 5, 2011·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Anil K ChaturvediMaura L Gillison
Nov 11, 2011·Archives of Toxicology·Christos T ChasapisMaria E Stefanidou
Feb 14, 2013·Viruses·Federico De Marco
Oct 12, 2013·The Laryngoscope·Shih-Han HungShiu-Dong Chung
Apr 4, 2014·Journal of Virology·Vonetta M WilliamsPenelope Duerksen-Hughes
Dec 15, 2015·Journal of the National Cancer Institute·Everett E VokesTanguy Y Seiwert
Jan 12, 2017·CA: a Cancer Journal for Clinicians·Kevin D ShieldIsabelle Soerjomataram

❮ Previous
Next ❯

Software Mentioned

SAS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.