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A Tandem Cell for Nanopore-based DNA Sequencing with Exonuclease

bioRxiv

Jun 4, 2014

G Sampath

Abstract

A tandem cell is proposed for DNA sequencing in which an exonuclease enzyme cleaves bases (mononucleotides) from a strand of DNA for identification inside a nanopore. It has two nanopores and three compartments with the structure [ cis 1, upstream nanopore (UNP), trans 1 = cis 2, downst...read more

Mentioned in this Paper

SOCS2 gene
SOCS1 gene
TC2N gene
USP4 protein, human
Gli protein, mouse
Sequencing
Cis, cis, cis, cis-(5.5.5.4)-1-azafenestrane
Nanopores
DNA, Double-Stranded
Cleaved Cell
14
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A Tandem Cell for Nanopore-based DNA Sequencing with Exonuclease

bioRxiv

Jun 4, 2014

G Sampath

PMID: 990005934

DOI: 10.1101/005934

Abstract

A tandem cell is proposed for DNA sequencing in which an exonuclease enzyme cleaves bases (mononucleotides) from a strand of DNA for identification inside a nanopore. It has two nanopores and three compartments with the structure [ cis 1, upstream nanopore (UNP), trans 1 = cis 2, downst...read more

Mentioned in this Paper

SOCS2 gene
SOCS1 gene
TC2N gene
USP4 protein, human
Gli protein, mouse
Sequencing
Cis, cis, cis, cis-(5.5.5.4)-1-azafenestrane
Nanopores
DNA, Double-Stranded
Cleaved Cell
14

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Paper Details
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