PMID: 9184456Jan 1, 1997Paper

A technique for measuring the compressive modulus of articular cartilage under physiological loading rates with preliminary results

Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
D E Shepherd, B B Seedhom

Abstract

This paper describes a technique and apparatus for measuring the compressive modulus of articular cartilage under physiological loading rates. The compressive modulus is the most relevant property to the primary function of articular cartilage i.e., load carriage. It has been determined previously from measurement of cartilage deformation under slow or almost static loading conditions. The modulus was based on deformations occurring 2 s after the initial application of load which greatly reduces its relevance since in physiological conditions joint loading occurs within 10-150 ms. Five human knee joints have been used to test the apparatus before a major study is undertaken. The preliminary results from these joints show that the compressive modulus of articular cartilage measured within physiological loading time intervals was much greater than previously reported. The compressive modulus at 20 ms was in the range 4.4-27 MPa and was between 32 and 75 per cent greater than its value obtained at 2 s after loading.

References

Jan 1, 1989·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·A C Swann, B B Seedhom
Sep 1, 1972·Journal of Biomechanics·W C HayesL F Mockros
Oct 1, 1971·Journal of Applied Physiology·W C Hayes, L F Mockros
Dec 1, 1971·Journal of Biomechanics·G E KempsonM A Freeman
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Nov 1, 1993·British Journal of Rheumatology·J Q Yao, B B Seedhom
Dec 1, 1926·Wilhelm Roux' Archiv Für Entwicklungsmechanik Der Organismen·Ernst Bär

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Citations

Jun 29, 2010·Biomechanics and Modeling in Mechanobiology·A Félix QuiñonezZ M Jin
Aug 29, 2013·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·Benjamin Pearson, Daniel M Espino
Dec 20, 2015·Bio-medical Materials and Engineering·J LourençoP A Rego
Oct 8, 2016·BMC Musculoskeletal Disorders·Duncan K TempleDaniel M Espino
Oct 16, 2003·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·F H Dar, R M Aspden
Dec 30, 2011·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·P S RamakrishnanJ A Martin
May 3, 2014·Computer Methods in Biomechanics and Biomedical Engineering·R MootanahH J Hillstrom
Jun 16, 2014·BMC Musculoskeletal Disorders·Daniel M EspinoDavid W L Hukins
Jun 6, 2009·BMC Musculoskeletal Disorders·Geoffrey R FulcherDuncan E T Shepherd
Jan 1, 2009·Archives of Histology and Cytology·Raphael ImerUrs Staufer
Mar 15, 2015·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·Hamid SadeghiDuncan E T Shepherd
May 20, 2018·Biomechanics and Modeling in Mechanobiology·M A BiltonR J Clarke
Sep 8, 2007·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·B B SeedhomL Guardamagna
Dec 6, 2012·Computer Methods in Biomechanics and Biomedical Engineering·J P JorgeA Gaspar
Jul 28, 2006·Journal of Applied Biomechanics·Yi-Chung LinBenjamin J Fregly
Aug 20, 2016·Computer Methods in Biomechanics and Biomedical Engineering·Qian LiuPengcheng Dou
Jan 15, 2019·Journal of Tissue Engineering and Regenerative Medicine·Konstantinos TheodoridisAristeidis Kritis
Jan 13, 2021·Scientific Reports·Zhengwei LiM Taher A Saif
Sep 22, 2009·Ultrasound in Medicine & Biology·Min-Hua LuLing Qin

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